Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | higBA (relBE)/COG4683-HTH_37 |
Location | 25725..26383 | Replicon | plasmid pDETAB7a |
Accession | NZ_CP077838 | ||
Organism | Acinetobacter baumannii strain DETAB-E159 |
Toxin (Protein)
Gene name | higB | Uniprot ID | - |
Locus tag | KU204_RS19335 | Protein ID | WP_000312250.1 |
Coordinates | 26024..26383 (-) | Length | 120 a.a. |
Antitoxin (Protein)
Gene name | higA | Uniprot ID | - |
Locus tag | KU204_RS19330 | Protein ID | WP_001096429.1 |
Coordinates | 25725..26024 (-) | Length | 100 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
KU204_RS19285 (KU204_19200) | 20758..21015 | + | 258 | WP_000834292.1 | hypothetical protein | - |
KU204_RS19290 (KU204_19205) | 21020..21592 | + | 573 | WP_038345812.1 | hypothetical protein | - |
KU204_RS19295 (KU204_19210) | 21568..21747 | + | 180 | WP_002081921.1 | hypothetical protein | - |
KU204_RS19300 (KU204_19215) | 21764..22393 | + | 630 | WP_002081923.1 | hypothetical protein | - |
KU204_RS19305 (KU204_19220) | 22433..22942 | + | 510 | WP_001043199.1 | hypothetical protein | - |
KU204_RS19310 (KU204_19225) | 23023..23577 | + | 555 | WP_038345807.1 | hypothetical protein | - |
KU204_RS19315 (KU204_19230) | 23627..24163 | + | 537 | WP_000731981.1 | hypothetical protein | - |
KU204_RS19320 (KU204_19235) | 24786..25268 | + | 483 | WP_001052677.1 | hypothetical protein | - |
KU204_RS19325 (KU204_19240) | 25361..25624 | - | 264 | WP_000110863.1 | hypothetical protein | - |
KU204_RS19330 (KU204_19245) | 25725..26024 | - | 300 | WP_001096429.1 | XRE family transcriptional regulator | Antitoxin |
KU204_RS19335 (KU204_19250) | 26024..26383 | - | 360 | WP_000312250.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
KU204_RS19340 (KU204_19255) | 26584..27150 | + | 567 | WP_000710385.1 | hypothetical protein | - |
KU204_RS19345 (KU204_19260) | 27199..27381 | + | 183 | WP_000373385.1 | hypothetical protein | - |
KU204_RS19350 (KU204_19265) | 27448..28146 | + | 699 | WP_000873188.1 | hypothetical protein | - |
KU204_RS19355 (KU204_19270) | 28285..28668 | + | 384 | WP_000654348.1 | hypothetical protein | - |
KU204_RS19360 (KU204_19275) | 28735..29493 | + | 759 | WP_001053128.1 | hypothetical protein | - |
KU204_RS19365 (KU204_19280) | 29545..29880 | + | 336 | WP_000653925.1 | hypothetical protein | - |
KU204_RS19370 (KU204_19285) | 30747..31061 | + | 315 | WP_000708715.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Non-Mobilizable plasmid | - | - | 1..72258 | 72258 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 120 a.a. Molecular weight: 13751.62 Da Isoelectric Point: 4.8212
>T208059 WP_000312250.1 NZ_CP077838:c26383-26024 [Acinetobacter baumannii]
MAWDVETTELFDSWLAEQDENAQDKILASLLVLSELGPNLGRPHVDTIKESKYPNMKEIRVQVKGHPIRGFFAFDPERKA
IVLCAGDKKGLNEKAFYKEMIKIADEQYEQYLRDNYGDK
MAWDVETTELFDSWLAEQDENAQDKILASLLVLSELGPNLGRPHVDTIKESKYPNMKEIRVQVKGHPIRGFFAFDPERKA
IVLCAGDKKGLNEKAFYKEMIKIADEQYEQYLRDNYGDK
Download Length: 360 bp
>T208059 NZ_CP103562:c46342-45968 [Escherichia coli O25b:H4-ST131]
ATGAAAACATTACCCGATACACTCGTACGGGAGGCATCGCGCTGCCCGTCTCCCGTCACCATCTGGCAGACTCTGCTCTC
CCGACTGCTGGGCCAGCATTACGGCCTTACACTGAATGACACACCGTTTGCCGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGTGATGCGGTGAATTTTCTCGTGGAAAAATACGCGCTGGTGCGTACCGACCAGCCGGGATTC
AGCACTTGTCCCCGCTCTCAGTTAATAAACAGTATTGATATCCTCCGGGCTCGCCGGGCGACCGGCCTGATGACCCGCGA
CAATTACAGAACGGTAAATAACATTACCCTGGGTAAGCATCCGGAGGCGAAATGA
ATGAAAACATTACCCGATACACTCGTACGGGAGGCATCGCGCTGCCCGTCTCCCGTCACCATCTGGCAGACTCTGCTCTC
CCGACTGCTGGGCCAGCATTACGGCCTTACACTGAATGACACACCGTTTGCCGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGTGATGCGGTGAATTTTCTCGTGGAAAAATACGCGCTGGTGCGTACCGACCAGCCGGGATTC
AGCACTTGTCCCCGCTCTCAGTTAATAAACAGTATTGATATCCTCCGGGCTCGCCGGGCGACCGGCCTGATGACCCGCGA
CAATTACAGAACGGTAAATAACATTACCCTGGGTAAGCATCCGGAGGCGAAATGA
Antitoxin
Download Length: 100 a.a. Molecular weight: 11012.93 Da Isoelectric Point: 10.4856
>AT208059 WP_001096429.1 NZ_CP077838:c26024-25725 [Acinetobacter baumannii]
MAKLNDIISKRSPESQQRIKKMANQMLLDINLSNLREELKISQAEIAKNLGVSQAAISKREKLGKDLKISSLKEYVEAMG
GKVRLDVELPNGKHVAISI
MAKLNDIISKRSPESQQRIKKMANQMLLDINLSNLREELKISQAEIAKNLGVSQAAISKREKLGKDLKISSLKEYVEAMG
GKVRLDVELPNGKHVAISI
Download Length: 300 bp
>AT208059 NZ_CP103562:c46800-46432 [Escherichia coli O25b:H4-ST131]
GTGTCAGACACACTCTCCGGGACAACGCATCCCGATGACAATCACGACCGTCCCTGGTGGGGACTACCCTGCACCGTGAC
GCCCTGTTTCGGCGCCCGTCTGGTGCAGGAGGGCAATCAGTTGCATTACCTTGCCGACCGCGCCGATATCAGAGGCCGGT
TCAGCGACGCGGATGCGTACCATCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAGCTCATGCTCACCAACGGT
GAACTGAATCCCCGCCATCAGCATACCGTGACACTGTATGCGAAGGGGCTGACCTGTGAAGCCGACACCCTCGGCTCCTG
TGGTTACGTTTATCTGGCTGTTTATCCGACACCCGAAATGAAAAATTAA
GTGTCAGACACACTCTCCGGGACAACGCATCCCGATGACAATCACGACCGTCCCTGGTGGGGACTACCCTGCACCGTGAC
GCCCTGTTTCGGCGCCCGTCTGGTGCAGGAGGGCAATCAGTTGCATTACCTTGCCGACCGCGCCGATATCAGAGGCCGGT
TCAGCGACGCGGATGCGTACCATCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAGCTCATGCTCACCAACGGT
GAACTGAATCCCCGCCATCAGCATACCGTGACACTGTATGCGAAGGGGCTGACCTGTGAAGCCGACACCCTCGGCTCCTG
TGGTTACGTTTATCTGGCTGTTTATCCGACACCCGAAATGAAAAATTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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