Detailed information of TA system TA207709

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 87446..87626
• Replicon: chromosome
• Accession: NZ_CP077757
• Organism: Staphylococcus aureus strain WHC07

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: KTR68_RS00580
• Protein ID: WP_001801861.1
• Coordinates: 87531..87626 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	87446..87503 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KTR68_RS00565	83092..83709	+	618	Protein_74	staphylococcal enterotoxin type O	-
KTR68_RS00570	83753..84925	-	1173	WP_000195429.1	IS256-like element IS256 family transposase	-
KTR68_RS13970	85185..85694	+	510	WP_224684909.1	hypothetical protein	-
KTR68_RS00575	85756..86880	+	1125	WP_223876714.1	hypothetical protein	-
KTR68_RS13975	87310..87408	-	99	Protein_78	hypothetical protein	-
-	87446..87503	+	58	-	-	Antitoxin
KTR68_RS00580	87531..87626	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
KTR68_RS00585	88078..88524	+	447	WP_000747805.1	DUF1433 domain-containing protein	-
KTR68_RS00590	88638..89264	+	627	Protein_81	ImmA/IrrE family metallo-endopeptidase	-
KTR68_RS00595	89396..90148	-	753	WP_000764922.1	staphylococcal enterotoxin type 27	-
KTR68_RS00600	90175..90858	-	684	WP_000957233.1	exotoxin beta-grasp domain-containing protein	-
KTR68_RS00605	90945..91571	-	627	WP_000669028.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	83753..84925	1172

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T207709 WP_001801861.1 NZ_CP077757:c87626-87531 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T207709 NZ_CP103480:141299-141604 [Escherichia coli]
ATGCAGTTTAAGGTTTACACCTATAAAAGAGAGAGCCGTTATCGTCTGTTTGTGGATGTCCAGAGTGACATTATTGACAC
GCCTGGGCGACGGATGGTGATCCCCCTGGCCAGTGCACGTCTGTTGTCAGATAAGGTCTCCCGTGAGCTTTACCCGGTGG
TGCATGTCGGGGATGAAAGCTGGCGCATGATGACCACCGATATGGCCAGTGTGCCGGTCTCCGTTATCGGGGAGGAAGTG
GCTGATCTCAGCCACCGAGAAAATGACATCAAAAATGCCATTAACCTGATGTTCTGGGGAATATAA

Antitoxin

Nucleotide

• Length: 58 bp

>AT207709 NZ_CP077757:87446-87503 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin