Detailed information of TA system TA207695

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 90006..90186
• Replicon: chromosome
• Accession: NZ_CP077755
• Organism: Staphylococcus aureus strain WHC09

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: KTR65_RS00595
• Protein ID: WP_001801861.1
• Coordinates: 90091..90186 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	90006..90063 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KTR65_RS00575	85294..86064	+	771	WP_000764689.1	staphylococcal enterotoxin type U	-
KTR65_RS00580	86103..86261	+	159	Protein_77	exotoxin	-
KTR65_RS00585	86313..87485	-	1173	WP_000195429.1	IS256-like element IS256 family transposase	-
KTR65_RS14155	87745..88254	+	510	WP_224684909.1	hypothetical protein	-
KTR65_RS00590	88316..89440	+	1125	WP_223876714.1	hypothetical protein	-
KTR65_RS14160	89870..89968	-	99	Protein_81	hypothetical protein	-
-	90006..90063	+	58	-	-	Antitoxin
KTR65_RS00595	90091..90186	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
KTR65_RS00600	90638..91084	+	447	WP_217838626.1	DUF1433 domain-containing protein	-
KTR65_RS00605	91198..91824	+	627	Protein_84	ImmA/IrrE family metallo-endopeptidase	-
KTR65_RS00610	91956..92708	-	753	WP_000764922.1	staphylococcal enterotoxin type 27	-
KTR65_RS00615	92735..93418	-	684	WP_000957233.1	exotoxin beta-grasp domain-containing protein	-
KTR65_RS00620	93505..94131	-	627	WP_000669028.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	86313..87485	1172

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T207695 WP_001801861.1 NZ_CP077755:c90186-90091 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T207695 NZ_CP103479:2954185-2954292 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin

Nucleotide

• Length: 58 bp

>AT207695 NZ_CP077755:90006-90063 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin