Detailed information of TA system TA207691

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-SprA2AS/-
• Location: 2601908..2602092
• Replicon: chromosome
• Accession: NZ_CP077741
• Organism: Staphylococcus aureus strain NL1

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: A0A2P7CQJ7
• Locus tag: KTE72_RS13070
• Protein ID: WP_000482647.1
• Coordinates: 2601985..2602092 (-)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprA2AS
Locus tag	-
Coordinates	2601908..2601968 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KTE72_RS13055 (KTE72_12955)	2597362..2597529	-	168	WP_001798790.1	hypothetical protein	-
KTE72_RS13060 (KTE72_12960)	2597760..2599493	-	1734	WP_000486511.1	ABC transporter ATP-binding protein	-
KTE72_RS13065 (KTE72_12965)	2599518..2601281	-	1764	WP_001064818.1	ABC transporter ATP-binding protein	-
-	2601908..2601968	+	61	-	-	Antitoxin
KTE72_RS13070 (KTE72_12970)	2601985..2602092	-	108	WP_000482647.1	type I toxin-antitoxin system Fst family toxin	Toxin
KTE72_RS13075 (KTE72_12975)	2602226..2602612	-	387	WP_000779355.1	flippase GtxA	-
KTE72_RS13080 (KTE72_12980)	2602879..2604021	+	1143	WP_001176859.1	glycerate kinase	-
KTE72_RS13085 (KTE72_12985)	2604081..2604740	+	660	WP_000831300.1	hypothetical protein	-
KTE72_RS13090 (KTE72_12990)	2604928..2606139	+	1212	WP_001191974.1	multidrug effflux MFS transporter	-
KTE72_RS13095 (KTE72_12995)	2606262..2606735	-	474	WP_000456489.1	GyrI-like domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 4012.76 Da
• Isoelectric Point: 10.4935

>T207691 WP_000482647.1 NZ_CP077741:c2602092-2601985 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Nucleotide

• Length: 108 bp

>T207691 NZ_CP103479:1296481-1296792 [Escherichia coli]
ATGCACATCATTTCGAAAGCGCCATTTGAAGAGTGTGCGCGCAAATATCCTAACGACGCTCTGGCTCTACACTCATTGTA
TCGGGTTATTAAGGAAACGGATTTTTCTACACCAGAAGAAATGCGAACGGCGTTTCCTAACCTCGACAATTTTAAATATC
GCAACAAATGGTACGTTCTGGATGTCGGCGGGAACAATCTTAGGGTTATTGCCTACATAAACTTTGTTAATAAGCGGTTC
TTTGTGAAGCACATAACGAATCACGCAGAGTATGACAAACTGACACGTTACTACAGAGAGAACAAAGAATGA

Antitoxin

Nucleotide

• Length: 61 bp

>AT207691 NZ_CP077741:2601908-2601968 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Structures

Toxin

• AlphaFold DB: A0A2P7CQJ7

Antitoxin