Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprG3-sprA1AS/-
Location 2226387..2226584 Replicon chromosome
Accession NC_003923
Organism Staphylococcus aureus subsp. aureus MW2

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag MW_RS11280 Protein ID WP_001802298.1
Coordinates 2226480..2226584 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 2226387..2226425 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MW_RS11260 (MW2068) 2222571..2223236 - 666 WP_001024095.1 SDR family oxidoreductase -
MW_RS11265 (MW2069) 2223388..2223708 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
MW_RS11270 (MW2070) 2223710..2224690 + 981 WP_000019743.1 CDF family zinc efflux transporter CzrB -
MW_RS11275 (MW2071) 2224956..2226047 + 1092 WP_000495683.1 hypothetical protein -
- 2226387..2226425 + 39 - - Antitoxin
MW_RS11280 2226480..2226584 - 105 WP_001802298.1 hypothetical protein Toxin
MW_RS14895 2227264..2227422 + 159 WP_001792784.1 hypothetical protein -
MW_RS11285 (MW2078) 2228081..2228938 - 858 WP_000370917.1 Cof-type HAD-IIB family hydrolase -
MW_RS11290 (MW2079) 2229006..2229788 - 783 WP_000908178.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T20742 WP_001802298.1 NC_003923:c2226584-2226480 [Staphylococcus aureus subsp. aureus MW2]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T20742 NC_003923:c2226584-2226480 [Staphylococcus aureus subsp. aureus MW2]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 39 bp

>AT20742 NC_003923:2226387-2226425 [Staphylococcus aureus subsp. aureus MW2]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References