Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1894021..1894203 Replicon chromosome
Accession NC_003923
Organism Staphylococcus aureus subsp. aureus MW2

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag MW_RS15155 Protein ID WP_001801861.1
Coordinates 1894021..1894116 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1894144..1894203 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MW_RS09280 (MW1739) 1889691..1890317 + 627 WP_000669017.1 hypothetical protein -
MW_RS09285 (MW1740) 1890358..1890699 + 342 WP_000627541.1 DUF3969 family protein -
MW_RS09290 (MW1741) 1890800..1891372 + 573 WP_000414202.1 hypothetical protein -
MW_RS09295 (MW1742) 1891570..1892127 - 558 Protein_1784 ImmA/IrrE family metallo-endopeptidase -
MW_RS09305 (MW1743) 1892501..1892677 - 177 WP_000375477.1 hypothetical protein -
MW_RS09310 (MW1744) 1892688..1893071 - 384 WP_000070811.1 hypothetical protein -
MW_RS09320 (MW1747) 1893675..1893818 - 144 WP_001549059.1 transposase -
MW_RS15155 1894021..1894116 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1894144..1894203 - 60 - - Antitoxin
MW_RS09325 1894239..1894340 + 102 WP_001791893.1 hypothetical protein -
MW_RS14780 1894318..1894494 - 177 Protein_1790 transposase -
MW_RS09330 (MW1748) 1894688..1895065 - 378 WP_001037045.1 DUF1433 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T20732 WP_001801861.1 NC_003923:1894021-1894116 [Staphylococcus aureus subsp. aureus MW2]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T20732 NC_003923:1894021-1894116 [Staphylococcus aureus subsp. aureus MW2]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 60 bp

>AT20732 NC_003923:c1894203-1894144 [Staphylococcus aureus subsp. aureus MW2]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References