Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) HipBST/HipA(toxin)
Location 4851063..4852414 Replicon chromosome
Accession NZ_CP077421
Organism Pectobacterium polaris strain QK413-1

Toxin (Protein)


Gene name HipT Uniprot ID -
Locus tag KSL88_RS21745 Protein ID WP_224072814.1
Coordinates 4851374..4852414 (+) Length 347 a.a.

Antitoxin (Protein)


Gene name HipS Uniprot ID -
Locus tag KSL88_RS21740 Protein ID WP_095701129.1
Coordinates 4851063..4851377 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KSL88_RS21720 (KSL88_21675) 4846679..4848367 + 1689 WP_224072811.1 ABC transporter ATP-binding protein -
KSL88_RS21725 (KSL88_21680) 4848400..4849434 + 1035 WP_224072812.1 putative FMN-dependent luciferase-like monooxygenase -
KSL88_RS21730 (KSL88_21685) 4849431..4850564 + 1134 WP_224072813.1 alkylhydroperoxidase domain protein -
KSL88_RS21735 (KSL88_21690) 4850752..4851078 + 327 WP_095701130.1 helix-turn-helix domain-containing protein -
KSL88_RS21740 (KSL88_21695) 4851063..4851377 + 315 WP_095701129.1 HipA N-terminal domain-containing protein Antitoxin
KSL88_RS21745 (KSL88_21700) 4851374..4852414 + 1041 WP_224072814.1 HipA domain-containing protein Toxin
KSL88_RS21750 (KSL88_21705) 4852474..4853097 - 624 WP_224072815.1 LysE family translocator -
KSL88_RS21755 (KSL88_21710) 4853352..4854107 + 756 WP_224072816.1 thiol:disulfide interchange protein DsbG -
KSL88_RS21760 (KSL88_21715) 4854141..4855046 - 906 WP_224072817.1 siderophore-interacting protein -
KSL88_RS21765 (KSL88_21720) 4855302..4855553 + 252 WP_010281712.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
KSL88_RS21770 (KSL88_21725) 4855550..4855837 + 288 WP_174866994.1 type II toxin-antitoxin system RelE/ParE family toxin -
KSL88_RS21775 (KSL88_21730) 4855940..4857292 - 1353 WP_224072818.1 glutathione-disulfide reductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(57-307)

Antitoxin

HipA, N-terminal subdomain 1

(6-98)


Sequences

Toxin        


Download         Length: 347 a.a.        Molecular weight: 39521.37 Da        Isoelectric Point: 6.4476

>T207196 WP_224072814.1 NZ_CP077421:4851374-4852414 [Pectobacterium polaris]
MTRCRILLTPLTHEEEIATGYSRKGLKHLTGSTHASSTLRFTRQQFMHDLPQAQKGMSISGYQPKIQMVLEERAFTVVDH
QGLYILKPSPIEFPHLAENEHATMTLMARLGFAVPPHGLLRFKPEQADDEPEFAFVIKRFDRDEQTGHPIHQEQLDGAMG
IGEKFGKIHTDGRQYVSYERLALFLSKHVNDNIVFKIDLFRRIAYAYMLGNNDMHLRNFGLIHSRSGSLMLAPIYDFVSV
APYPTYFSSCFMALPLLIQEEGDEALAPGFETAYGEYLGMDFILFGQRIGLSENLTKKLLADFLKEAECVESTYRDSFMP
ADAIETTLRCYRHRLNLMSILDAERI

Download         Length: 1041 bp

>T207196 NZ_CP102932:3577205-3577504 [Enterobacter sp. Crenshaw]
ATGATTAGTTATTTTCGGGATCAATGGCTTGAGGATTTTTTTCTTTACGGCAGATCGAGCAATGTTATTCCTGCAAATCT
GGAAACAGCGCTTGCGAGAAAGCTCGATATCATCAGGGCAGCAACCTCGCACAGGGATTTGCGATCGCCACCGGGCAATA
TGTATGAAGCATTGAATCCTCCGCTGAAGGGATATTCCTCAATCCGGGTAAACAGGCAATACAGGCTCGTATTTCGCTGG
ACAGAGGGTAAAGCAGAAGATCTCTACCTCTCTCCACACAAGTACACGCAACACAAGTGA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11887.66 Da        Isoelectric Point: 9.2317

>AT207196 WP_095701129.1 NZ_CP077421:4851063-4851377 [Pectobacterium polaris]
MRRQVKVYLYGVHIGQLSQDDEGYLFEYKKSYIGPPLSLSLPIQTGTFRSKTLPPYFASLAPEGWLRRQYSQLQHLDEKD
LFGILIQNGKNLIGAVQLIAEDKS

Download         Length: 315 bp

>AT207196 NZ_CP102932:3577515-3577862 [Enterobacter sp. Crenshaw]
ATGACACTTCAACAGGCACTCCGCAAACCCACCACGCCGGGCGACGTGTTGCAGTATGAGTATCTTGAACCGCTCAATCT
GAAAATCAGCGATCTGGCGGAGATGCTCAATGTTCACCGCAACACCATCAGCGCGCTGGTCAATAACAATCGCAAGCTGA
CTGCCGATATGGCGATCAAACTGGCAAAAGCCTTTGATACCACGATTGAATTTTGGCTTAACTTACAGCTGAACGTCGAT
ATCTGGGAAGCTCAATCCAACCCCAGGACGCAGGAGGAGCTAAGCCGTATAAAGACCGTTGCGGACGTCATGGCTAAGCG
AAAATCTGGCCAGCCGGATGTAGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References