Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | HipBST/HipA(toxin) |
| Location | 4851063..4852414 | Replicon | chromosome |
| Accession | NZ_CP077421 | ||
| Organism | Pectobacterium polaris strain QK413-1 | ||
Toxin (Protein)
| Gene name | HipT | Uniprot ID | - |
| Locus tag | KSL88_RS21745 | Protein ID | WP_224072814.1 |
| Coordinates | 4851374..4852414 (+) | Length | 347 a.a. |
Antitoxin (Protein)
| Gene name | HipS | Uniprot ID | - |
| Locus tag | KSL88_RS21740 | Protein ID | WP_095701129.1 |
| Coordinates | 4851063..4851377 (+) | Length | 105 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KSL88_RS21720 (KSL88_21675) | 4846679..4848367 | + | 1689 | WP_224072811.1 | ABC transporter ATP-binding protein | - |
| KSL88_RS21725 (KSL88_21680) | 4848400..4849434 | + | 1035 | WP_224072812.1 | putative FMN-dependent luciferase-like monooxygenase | - |
| KSL88_RS21730 (KSL88_21685) | 4849431..4850564 | + | 1134 | WP_224072813.1 | alkylhydroperoxidase domain protein | - |
| KSL88_RS21735 (KSL88_21690) | 4850752..4851078 | + | 327 | WP_095701130.1 | helix-turn-helix domain-containing protein | - |
| KSL88_RS21740 (KSL88_21695) | 4851063..4851377 | + | 315 | WP_095701129.1 | HipA N-terminal domain-containing protein | Antitoxin |
| KSL88_RS21745 (KSL88_21700) | 4851374..4852414 | + | 1041 | WP_224072814.1 | HipA domain-containing protein | Toxin |
| KSL88_RS21750 (KSL88_21705) | 4852474..4853097 | - | 624 | WP_224072815.1 | LysE family translocator | - |
| KSL88_RS21755 (KSL88_21710) | 4853352..4854107 | + | 756 | WP_224072816.1 | thiol:disulfide interchange protein DsbG | - |
| KSL88_RS21760 (KSL88_21715) | 4854141..4855046 | - | 906 | WP_224072817.1 | siderophore-interacting protein | - |
| KSL88_RS21765 (KSL88_21720) | 4855302..4855553 | + | 252 | WP_010281712.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| KSL88_RS21770 (KSL88_21725) | 4855550..4855837 | + | 288 | WP_174866994.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| KSL88_RS21775 (KSL88_21730) | 4855940..4857292 | - | 1353 | WP_224072818.1 | glutathione-disulfide reductase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 347 a.a. Molecular weight: 39521.37 Da Isoelectric Point: 6.4476
>T207196 WP_224072814.1 NZ_CP077421:4851374-4852414 [Pectobacterium polaris]
MTRCRILLTPLTHEEEIATGYSRKGLKHLTGSTHASSTLRFTRQQFMHDLPQAQKGMSISGYQPKIQMVLEERAFTVVDH
QGLYILKPSPIEFPHLAENEHATMTLMARLGFAVPPHGLLRFKPEQADDEPEFAFVIKRFDRDEQTGHPIHQEQLDGAMG
IGEKFGKIHTDGRQYVSYERLALFLSKHVNDNIVFKIDLFRRIAYAYMLGNNDMHLRNFGLIHSRSGSLMLAPIYDFVSV
APYPTYFSSCFMALPLLIQEEGDEALAPGFETAYGEYLGMDFILFGQRIGLSENLTKKLLADFLKEAECVESTYRDSFMP
ADAIETTLRCYRHRLNLMSILDAERI
MTRCRILLTPLTHEEEIATGYSRKGLKHLTGSTHASSTLRFTRQQFMHDLPQAQKGMSISGYQPKIQMVLEERAFTVVDH
QGLYILKPSPIEFPHLAENEHATMTLMARLGFAVPPHGLLRFKPEQADDEPEFAFVIKRFDRDEQTGHPIHQEQLDGAMG
IGEKFGKIHTDGRQYVSYERLALFLSKHVNDNIVFKIDLFRRIAYAYMLGNNDMHLRNFGLIHSRSGSLMLAPIYDFVSV
APYPTYFSSCFMALPLLIQEEGDEALAPGFETAYGEYLGMDFILFGQRIGLSENLTKKLLADFLKEAECVESTYRDSFMP
ADAIETTLRCYRHRLNLMSILDAERI
Download Length: 1041 bp
>T207196 NZ_CP102932:3577205-3577504 [Enterobacter sp. Crenshaw]
ATGATTAGTTATTTTCGGGATCAATGGCTTGAGGATTTTTTTCTTTACGGCAGATCGAGCAATGTTATTCCTGCAAATCT
GGAAACAGCGCTTGCGAGAAAGCTCGATATCATCAGGGCAGCAACCTCGCACAGGGATTTGCGATCGCCACCGGGCAATA
TGTATGAAGCATTGAATCCTCCGCTGAAGGGATATTCCTCAATCCGGGTAAACAGGCAATACAGGCTCGTATTTCGCTGG
ACAGAGGGTAAAGCAGAAGATCTCTACCTCTCTCCACACAAGTACACGCAACACAAGTGA
ATGATTAGTTATTTTCGGGATCAATGGCTTGAGGATTTTTTTCTTTACGGCAGATCGAGCAATGTTATTCCTGCAAATCT
GGAAACAGCGCTTGCGAGAAAGCTCGATATCATCAGGGCAGCAACCTCGCACAGGGATTTGCGATCGCCACCGGGCAATA
TGTATGAAGCATTGAATCCTCCGCTGAAGGGATATTCCTCAATCCGGGTAAACAGGCAATACAGGCTCGTATTTCGCTGG
ACAGAGGGTAAAGCAGAAGATCTCTACCTCTCTCCACACAAGTACACGCAACACAAGTGA
Antitoxin
Download Length: 105 a.a. Molecular weight: 11887.66 Da Isoelectric Point: 9.2317
>AT207196 WP_095701129.1 NZ_CP077421:4851063-4851377 [Pectobacterium polaris]
MRRQVKVYLYGVHIGQLSQDDEGYLFEYKKSYIGPPLSLSLPIQTGTFRSKTLPPYFASLAPEGWLRRQYSQLQHLDEKD
LFGILIQNGKNLIGAVQLIAEDKS
MRRQVKVYLYGVHIGQLSQDDEGYLFEYKKSYIGPPLSLSLPIQTGTFRSKTLPPYFASLAPEGWLRRQYSQLQHLDEKD
LFGILIQNGKNLIGAVQLIAEDKS
Download Length: 315 bp
>AT207196 NZ_CP102932:3577515-3577862 [Enterobacter sp. Crenshaw]
ATGACACTTCAACAGGCACTCCGCAAACCCACCACGCCGGGCGACGTGTTGCAGTATGAGTATCTTGAACCGCTCAATCT
GAAAATCAGCGATCTGGCGGAGATGCTCAATGTTCACCGCAACACCATCAGCGCGCTGGTCAATAACAATCGCAAGCTGA
CTGCCGATATGGCGATCAAACTGGCAAAAGCCTTTGATACCACGATTGAATTTTGGCTTAACTTACAGCTGAACGTCGAT
ATCTGGGAAGCTCAATCCAACCCCAGGACGCAGGAGGAGCTAAGCCGTATAAAGACCGTTGCGGACGTCATGGCTAAGCG
AAAATCTGGCCAGCCGGATGTAGCCTGA
ATGACACTTCAACAGGCACTCCGCAAACCCACCACGCCGGGCGACGTGTTGCAGTATGAGTATCTTGAACCGCTCAATCT
GAAAATCAGCGATCTGGCGGAGATGCTCAATGTTCACCGCAACACCATCAGCGCGCTGGTCAATAACAATCGCAAGCTGA
CTGCCGATATGGCGATCAAACTGGCAAAAGCCTTTGATACCACGATTGAATTTTGGCTTAACTTACAGCTGAACGTCGAT
ATCTGGGAAGCTCAATCCAACCCCAGGACGCAGGAGGAGCTAAGCCGTATAAAGACCGTTGCGGACGTCATGGCTAAGCG
AAAATCTGGCCAGCCGGATGTAGCCTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|