Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 28243..28900 Replicon chromosome
Accession NZ_CP077421
Organism Pectobacterium polaris strain QK413-1

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag KSL88_RS00125 Protein ID WP_174866779.1
Coordinates 28529..28900 (-) Length 124 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag KSL88_RS00120 Protein ID WP_224072873.1
Coordinates 28243..28542 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KSL88_RS00100 (KSL88_00100) 23496..24485 + 990 WP_224072870.1 nucleoside hydrolase -
KSL88_RS00105 (KSL88_00105) 24485..25462 + 978 WP_095993309.1 ABC transporter permease -
KSL88_RS00110 (KSL88_00110) 25459..26367 + 909 WP_224072871.1 ABC transporter permease -
KSL88_RS00115 (KSL88_00115) 26407..28206 + 1800 WP_224072872.1 ABC transporter ATP-binding protein -
KSL88_RS00120 (KSL88_00120) 28243..28542 - 300 WP_224072873.1 XRE family transcriptional regulator Antitoxin
KSL88_RS00125 (KSL88_00125) 28529..28900 - 372 WP_174866779.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
KSL88_RS00130 (KSL88_00130) 29238..29936 + 699 WP_224073919.1 D-galactonate utilization transcriptional regulator DgoR -
KSL88_RS00135 (KSL88_00135) 29933..30829 + 897 WP_095701018.1 2-dehydro-3-deoxygalactonokinase -
KSL88_RS00140 (KSL88_00140) 30813..31430 + 618 WP_095993313.1 2-dehydro-3-deoxy-6-phosphogalactonate aldolase -
KSL88_RS00145 (KSL88_00145) 31427..32575 + 1149 WP_005976723.1 galactonate dehydratase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(14-108)

Antitoxin

Cro/C1-type helix-turn-helix domain

(32-80)


Sequences

Toxin        


Download         Length: 124 a.a.        Molecular weight: 14130.06 Da        Isoelectric Point: 4.8510

>T207184 WP_174866779.1 NZ_CP077421:c28900-28529 [Pectobacterium polaris]
MAWEIVTRALFDIWFDEQTEAVQEEVLAHLAILEEDGPQLGRPQVDQIKGSKYKNMKELRVQVGGHPYRTFFAFDRTRKA
IILCAGDKKGEDEKLFYERMIKIADAEFTSHLISPEAKEDGNA

Download         Length: 372 bp

>T207184 NZ_CP102929:2124513-2124764 [Pseudomonas sp. CBS]
GTGTCGAAAAATGAAAAGCTGCTGGCCAAACTGCTCAATGAACAATCGGCTTTTACCTGGGCCGAACGGGTAACGCTGCT
GCGGCGACTGGGCTACACGCAAATCGAAGGCGCGGGTAGCCGAGTCAGGTTCGACATAGGCGACCCCAGTGCAATGATCA
CCTTGCACAAGCCTCACCCCGGCAACGAACTGAAACACTACATTCGGCGCCAAATCATCGAACAATTGAAATCAGGAGAA
CTGATTCAGTGA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 11049.02 Da        Isoelectric Point: 10.3388

>AT207184 WP_224072873.1 NZ_CP077421:c28542-28243 [Pectobacterium polaris]
MATLKEMMAKRSPESRARIEARTAEIRQEITLAKLREELNMSQTQLALALGVKQPSIVKMEKVENDPKLSTLKRYVTALG
GELTLDVTLPDGKRIALTL

Download         Length: 300 bp

>AT207184 NZ_CP102929:2124761-2125117 [Pseudomonas sp. CBS]
GTGAACAACCAGCTGAAACACAAAGGCTACATCGGCTCCATCGAAGCCAGCCTCGAAGACAACTGCCTCTTCGGAAAGCT
GCTTTTCATCAAGGCCCTGGTCAGCTACGAGGGGAAAACCGTCGCCGAACTGGATACGGCCTTTTGCACCGCCGTGGACG
ACTACATCGAGACCTGCATGGCCCTTGGGCAAACACCGGAAAAGCCCTGCAAGGGCTCGTTCAACGTCCGTGTCGGCCAT
GACCTCCATTTGGCCGCCGCCCTCGCGGCGACCCGGCAAAAAGTCACGCTGAACGACCTCACACGGCAAGCGCTGAACGA
ATTCCTGCAACATCGCGGCGCACTCGTTGCCGGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References