Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 59122..59630 Replicon plasmid unnamed1
Accession NZ_CP077408
Organism Enterobacter roggenkampii strain FDAARGOS 1430

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag I6L60_RS22705 Protein ID WP_069599006.1
Coordinates 59122..59388 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag I6L60_RS22710 Protein ID WP_069599005.1
Coordinates 59385..59630 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6L60_RS23405 54290..54577 + 288 WP_254210612.1 hypothetical protein -
I6L60_RS22680 (I6L60_22680) 54595..55194 + 600 WP_069599009.1 type IV conjugative transfer system lipoprotein TraV -
I6L60_RS22685 (I6L60_22685) 55205..57796 + 2592 WP_084833313.1 type IV secretion system protein TraC -
I6L60_RS22690 (I6L60_22690) 57793..58251 + 459 WP_084833312.1 type-F conjugative transfer system protein TrbI -
I6L60_RS22695 (I6L60_22695) 58251..58883 + 633 WP_069599007.1 type-F conjugative transfer system protein TraW -
I6L60_RS22700 (I6L60_22700) 58905..59081 + 177 WP_157888839.1 hypothetical protein -
I6L60_RS22705 (I6L60_22705) 59122..59388 - 267 WP_069599006.1 Txe/YoeB family addiction module toxin Toxin
I6L60_RS22710 (I6L60_22710) 59385..59630 - 246 WP_069599005.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
I6L60_RS22715 (I6L60_22715) 59712..60716 + 1005 WP_069599004.1 conjugal transfer pilus assembly protein TraU -
I6L60_RS22720 (I6L60_22720) 60727..61095 + 369 WP_069599003.1 hypothetical protein -
I6L60_RS22725 (I6L60_22725) 61092..61706 + 615 WP_069599002.1 type-F conjugative transfer system pilin assembly protein TrbC -
I6L60_RS22730 (I6L60_22730) 61703..63541 + 1839 WP_069599001.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
I6L60_RS22735 (I6L60_22735) 63538..64308 + 771 WP_069599000.1 type-F conjugative transfer system pilin assembly protein TraF -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - - 1..151584 151584


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-85)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10585.10 Da        Isoelectric Point: 10.2096

>T207162 WP_069599006.1 NZ_CP077408:c59388-59122 [Enterobacter roggenkampii]
MKTRFTRRGAADYQYWKDNNAKLFERVRQLILAIHADPFNGIGKPERLRHYKNPALYSRRIDREHRLVYSMANGELTIVA
CRYHYDDI

Download         Length: 267 bp

>T207162 NZ_CP102922:52754-53224 [Klebsiella quasipneumoniae]
GTGATCCTCTACAGGCTGACGAAAACAAAGTATCTTTCTACGGCCTGGACCGGATATGGTGCGAAAGAGGCTGGTGGGCG
CTGGAATAGCGTGGGGGTGTCAATGGTATATGTCTCCGAAACAGCATCACTAACGATGCTGGAGACGCTGGTACACCTGC
ATGCGGCACAGATAATGGACTCTTTCACGCTACTGAGTATCGATGTGCCTGATGAACTGATCCAAAGCGCAAACATGGAT
GAATTACCGGACAACTGGGCTGATGAGGATGCGCCTCAGGAACTGGCTGATTACGGAGATGCCTGGTCATTTACCAGGAG
CTCGGTTGCACTGCGTGTTCCCTCAGCCTTATCGCCGGTAGAGTTCAATTATCTGTTAAATCCTGAGCACCCTGAGTTTT
ACGGGATCGTGCAGAAGGCTCAACAGATACCGTTCCGGTTTGATAGTCGTCTTAAACCTGACAGGAAGTGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9110.13 Da        Isoelectric Point: 4.1344

>AT207162 WP_069599005.1 NZ_CP077408:c59630-59385 [Enterobacter roggenkampii]
MQALTFTEARRHFAETMQQVSDNAEPVRILRRDAPDVVIIDASEYDAIMETLHLFSNPANAAHINASLEELDRGDITEID
V

Download         Length: 246 bp

>AT207162 NZ_CP102922:52314-52757 [Klebsiella quasipneumoniae]
ATGAAAACTTTTAGTTTGTCCTCAAGTCCAGCCAGACCACAGCGCCTCTGGCAGGTTGCCGGGTTAAATAATGCTGATGG
TGTAGCGCTCCTGGGCCAAATCAATGAAGGCCTGGACGGGAAGGTGGTGAACCGGATCACTGACTGGGCCAGAATAACCC
AGAATGACCTGAGAAAAATGTCCGGTATCCCGTCAACCACATTTAGCCGCAGTGTGAAGGCACGTTTTAACCCGGAACAA
AGTGAACGTCTGGTACGGATTATCCGCGTTATTGATCGGGCGGTAGATTTGTTTGAAGGCGACAGGGAAGCCGCACAGAA
GTGGTTGAACGAACCTAACCGGGCATTGAGCTGGAAAGTGCCAGCAGACCTGATGGCATCCGAAACTGGAGCCTATGAGG
TCATTAAGCTGATTACGCGTCTGGAGCATGGGGTGTACTCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References