Detailed information of TA system TA207057

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): higBA (relBE)/HigB-HigA
• Location: 2855204..2855931
• Replicon: chromosome
• Accession: NZ_CP077331
• Organism: Lelliottia amnigena strain FDAARGOS 1446

Toxin (Protein)

• Gene name: higB
• Uniprot ID: -
• Locus tag: I6L76_RS13810
• Protein ID: WP_131486857.1
• Coordinates: 2855204..2855515 (+)
• Length: 104 a.a.

Antitoxin (Protein)

• Gene name: higA
• Uniprot ID: -
• Locus tag: I6L76_RS13815
• Protein ID: WP_174342747.1
• Coordinates: 2855512..2855931 (+)
• Length: 140 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, mRNA interferase HigB (22-93)

Antitoxin

• Cro/C1-type helix-turn-helix domain (85-138)

Sequences

Toxin

Protein

• Length: 104 a.a.
• Molecular weight: 12423.23 Da
• Isoelectric Point: 9.5047

>T207057 WP_131486857.1 NZ_CP077331:2855204-2855515 [Lelliottia amnigena]
MHVISKEPFEEAAKHYPNDSLALLALYRLLRETDFISPTELRTLIPSLDNFKYRSKWWVIDVGGNNLRIVAYINFVNKRF
YVKHIVTHSEYDKLNRYYRENKE

Nucleotide

• Length: 312 bp

>T207057 NZ_CP102866:482488-482838 [Bacillus velezensis]
TTGATTGTAAAGCGCGGCGATGTTTATTTTGCTGATTTATCTCCTGTTGTTGGCTCAGAGCAAGGCGGCGTACGCCCGGT
TTTAGTGATCCAAAATGATATCGGAAATCGCTTTAGCCCGACTGCTATTGTTGCAGCCATAACAGCCCAAATACAGAAAG
CGAAATTACCAACCCACGTCGAAATTGATGCAAAACGCTACGGTTTTGAAAGAGATTCCGTTATTTTGCTGGAGCAAATT
CGGACGATTGACAAGCAAAGATTAACGGATAAAATAACTCATCTGGATGATGAAATGATGGATAAGGTTGATGAAGCCTT
GCAAATCAGTTTGGCACTCATTGATTTTTAG

Antitoxin

Protein

• Length: 140 a.a.
• Molecular weight: 15431.47 Da
• Isoelectric Point: 4.4202

>AT207057 WP_174342747.1 NZ_CP077331:2855512-2855931 [Lelliottia amnigena]
MIANTARAIEATKQLVDAVPFLGGSSSESDYREALALVDYLIENDDENPLIDFLASKIADYENNSDRFAEFNKSVAEMPV
GVALLRTLIDQYKLSYADLKEEIGSKSLVSQILSGQRSLTITHIKALSARFGVRPEWFL

Nucleotide

• Length: 420 bp

>AT207057 NZ_CP102866:482201-482482 [Bacillus velezensis]
TTGTCTGAATCCAGCGCAAGAACCGAAATGAAAATCAGCTTGCCTGAAAACTTAGTAGCTGAATTGGATGGTGTAGCGAT
GCGGGAGAAACGAAGCAGAAACGAACTGATATCACAAGCAGTGAGAGCGTATGTCAGCGAACGGACAACTCGCCATAACC
GTGATTTGATGAGACGCGGGTATATGGAAATGGCGAAAATCAACTTGAATATCTCTTCTGAGGCTCACTATGCTGAGTGC
GAAGCAGAAACGACCGTTGAGCGCTTAGTCAGCGGAGGATAA