Detailed information of TA system TA206922

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-sprA1AS/-
• Location: 703070..703218
• Replicon: chromosome
• Accession: NZ_CP077270
• Organism: Staphylococcus haemolyticus strain FDAARGOS 1453

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: -
• Locus tag: I6L83_RS03525
• Protein ID: WP_011276848.1
• Coordinates: 703070..703165 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	703183..703218 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
I6L83_RS03490 (I6L83_03490)	698797..699030	+	234	WP_016931184.1	hypothetical protein	-
I6L83_RS03495 (I6L83_03495)	699138..699455	-	318	Protein_677	IS200/IS605-like element ISSep3 family transposase	-
I6L83_RS12515	700280..700405	+	126	WP_031886468.1	hypothetical protein	-
I6L83_RS03505 (I6L83_03505)	701009..701539	+	531	WP_011276845.1	N-acetyltransferase	-
I6L83_RS03510 (I6L83_03510)	701779..702162	+	384	WP_011276846.1	effector binding domain-containing protein	-
I6L83_RS03515 (I6L83_03515)	702301..702561	+	261	WP_011276847.1	hypothetical protein	-
I6L83_RS03520 (I6L83_03520)	702729..702875	+	147	WP_000668388.1	hypothetical protein	-
I6L83_RS03525 (I6L83_03525)	703070..703165	+	96	WP_011276848.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	703183..703218	+	36	-	-	Antitoxin
I6L83_RS03530 (I6L83_03530)	703359..704261	+	903	WP_057504751.1	nucleotidyltransferase	-
I6L83_RS03535 (I6L83_03535)	704265..704867	+	603	WP_011276850.1	hypothetical protein	-
I6L83_RS03540 (I6L83_03540)	705011..705094	-	84	Protein_686	ATP-binding protein	-
I6L83_RS03545 (I6L83_03545)	705095..705631	-	537	WP_057504750.1	hypothetical protein	-
I6L83_RS03550 (I6L83_03550)	705645..706226	-	582	WP_011276564.1	TetR family transcriptional regulator C-terminal domain-containing protein	-
I6L83_RS03555 (I6L83_03555)	706431..707009	+	579	WP_037559009.1	recombinase family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	SCCmec	-	tufA / clpC	473961..830283	356322
	-	flank	IS/Tn	-	-	699135..699455	320

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3623.38 Da
• Isoelectric Point: 9.5124

>T206922 WP_011276848.1 NZ_CP077270:703070-703165 [Staphylococcus haemolyticus]
MLEILVHITTTVISGCIIALFTHWLRNRKDK

Nucleotide

• Length: 96 bp

>T206922 NZ_CP102756:c4605337-4604819 [Salmonella enterica subsp. enterica serovar Kentucky]
GTGGACAACCTGACAATAGAGATTCTGGCTGATAACGCAGAATACAACTGGCGGCAGTTCGACTGCGGTGAGGCATCATT
AAACCTTTTTTTAACGCAGCATCTTCAGCGCCAGCATAACAACAAAATCTTGCGCGGTTATGTACTCAGAACCACTACGC
CAGAACGGCGAGTGTTGGGGTATTACACCCTGTCAGGAAGCTGCTTTGAACGCGCGTCGTTGCCTTCCAGAACCCAGCAA
AAGCGCATCCCTTACCAGAATATCCCCAGCGTTACGCTGGGCCGTTTAGCGGTCGATCTCTCATTACAGGGAAAAGGGTG
GGGAGCTATATTGGTCACGCATGCGATGAAAGTGGTGTGGTCGGCATCACTGGCCGTTGGGATTCATGGCATCTTTGTGG
AAGCGTTAAACGAAAAAGCCCAGGCCTTTTATCAGCGGCTGGGCTTTATTTCTTTATCCGGAGAAAACGAGCACGCGCTG
TTTTACCCGACAAAGTCGATTGAGCAACTTTTTGGCTAG

Antitoxin

Nucleotide

• Length: 36 bp

>AT206922 NZ_CP077270:703183-703218 [Staphylococcus haemolyticus]
TACAAAAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin