Detailed information of TA system TA206758

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-SprA2AS/-
• Location: 2599903..2600087
• Replicon: chromosome
• Accession: NZ_CP077098
• Organism: Staphylococcus aureus strain RGB-095930

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: -
• Locus tag: KSF82_RS13250
• Protein ID: WP_047527328.1
• Coordinates: 2599980..2600087 (-)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprA2AS
Locus tag	-
Coordinates	2599903..2599963 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KSF82_RS13235	2595358..2595525	-	168	WP_070974188.1	hypothetical protein	-
KSF82_RS13240	2595756..2597489	-	1734	WP_089535280.1	ABC transporter ATP-binding protein	-
KSF82_RS13245	2597514..2599277	-	1764	WP_001064818.1	ABC transporter ATP-binding protein	-
-	2599903..2599963	+	61	-	-	Antitoxin
KSF82_RS13250	2599980..2600087	-	108	WP_047527328.1	type I toxin-antitoxin system Fst family toxin	Toxin
KSF82_RS13255	2600221..2600607	-	387	WP_089535281.1	flippase GtxA	-
KSF82_RS13260	2600874..2602016	+	1143	WP_089535282.1	glycerate kinase	-
KSF82_RS13265	2602076..2602735	+	660	WP_000831300.1	hypothetical protein	-
KSF82_RS13270	2602923..2604134	+	1212	WP_089535283.1	multidrug effflux MFS transporter	-
KSF82_RS13275	2604257..2604730	-	474	WP_089535284.1	GyrI-like domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 4012.76 Da
• Isoelectric Point: 10.4935

>T206758 WP_047527328.1 NZ_CP077098:c2600087-2599980 [Staphylococcus aureus]
MFNLLIDIMTSAISGCLVAFFAHWLRTRNNKKGDK

Nucleotide

• Length: 108 bp

>T206758 NZ_CP102675:4711057-4711308 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTTATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGTTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATTATTGAGTGA

Antitoxin

Nucleotide

• Length: 61 bp

>AT206758 NZ_CP077098:2599903-2599963 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Structures

Antitoxin