Detailed information of TA system TA206756

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 2318151..2318368
• Replicon: chromosome
• Accession: NZ_CP077098
• Organism: Staphylococcus aureus strain RGB-095930

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: Q2FWA7
• Locus tag: KSF82_RS11795
• Protein ID: WP_001802298.1
• Coordinates: 2318264..2318368 (-)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprF4
Locus tag	-
Coordinates	2318151..2318206 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KSF82_RS11775	2314290..2314955	-	666	WP_001024099.1	SDR family oxidoreductase	-
KSF82_RS11780	2315107..2315427	+	321	WP_000003759.1	Zn(II)-responsive metalloregulatory transcriptional repressor CzrA	-
KSF82_RS11785	2315429..2316409	+	981	WP_000019735.1	CDF family zinc efflux transporter CzrB	-
KSF82_RS11790	2316675..2317766	+	1092	WP_000495673.1	hypothetical protein	-
-	2318151..2318206	+	56	-	-	Antitoxin
KSF82_RS11795	2318264..2318368	-	105	WP_001802298.1	hypothetical protein	Toxin
KSF82_RS11800	2319048..2319206	+	159	WP_001792784.1	hypothetical protein	-
KSF82_RS11805	2319864..2320721	-	858	WP_089535735.1	HAD family hydrolase	-
KSF82_RS11810	2320789..2321571	-	783	WP_000908191.1	ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3906.77 Da
• Isoelectric Point: 5.5724

>T206756 WP_001802298.1 NZ_CP077098:c2318368-2318264 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Nucleotide

• Length: 105 bp

>T206756 NZ_CP102675:3871303-3871638 [Escherichia coli]
ATGGTAAGCCGATACGTACCCGATATGGGCGATCTGATTTGGGTTGATTTTGACCCGACAAAAGGTAGCGAGCAAGCTGG
ACATCGTCCAGCTGTTGTCCTGAGTCCTTTCATGTACAACAACAAAACAGGTATGTGTCTGTGTGTTCCTTATACAACGC
AATCAAAAGGATATCCGTTCGAAGTTGTTTTATCCGGTCAGGAACGTGATGGCGTAGCGTTAGCTGATCAGGTAAAAAGT
ATCGCCTGGCGGGCAAGAGGAGCAACGAAGAAAGGAACAGTTGCCCCAGAGGAATTACAACTCATTAAAGCCAAAATTAA
CGTACTGATTGGGTAG

Antitoxin

Nucleotide

• Length: 56 bp

>AT206756 NZ_CP077098:2318151-2318206 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Structures

Toxin

• AlphaFold DB: A0A2I7Y9L9

Antitoxin