Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | higBA (relBE)/HigB-HigA |
Location | 4331005..4331596 | Replicon | chromosome |
Accession | NZ_CP077091 | ||
Organism | Pseudomonas hamedanensis strain SWRI65 |
Toxin (Protein)
Gene name | higB | Uniprot ID | - |
Locus tag | HU739_RS18755 | Protein ID | WP_186549755.1 |
Coordinates | 4331005..4331283 (+) | Length | 93 a.a. |
Antitoxin (Protein)
Gene name | graA | Uniprot ID | - |
Locus tag | HU739_RS18760 | Protein ID | WP_186549696.1 |
Coordinates | 4331291..4331596 (+) | Length | 102 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
HU739_RS18745 (HU739_018745) | 4327980..4329194 | + | 1215 | WP_186549700.1 | aldose 1-epimerase family protein | - |
HU739_RS18750 (HU739_018750) | 4329191..4330684 | - | 1494 | WP_186549698.1 | YifB family Mg chelatase-like AAA ATPase | - |
HU739_RS18755 (HU739_018755) | 4331005..4331283 | + | 279 | WP_186549755.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
HU739_RS18760 (HU739_018760) | 4331291..4331596 | + | 306 | WP_186549696.1 | HigA family addiction module antitoxin | Antitoxin |
HU739_RS18765 (HU739_018765) | 4331710..4331970 | - | 261 | WP_186549694.1 | accessory factor UbiK family protein | - |
HU739_RS18770 (HU739_018770) | 4332364..4332702 | + | 339 | WP_002555808.1 | P-II family nitrogen regulator | - |
HU739_RS18775 (HU739_018775) | 4332740..4334077 | + | 1338 | WP_186549692.1 | ammonium transporter | - |
HU739_RS18780 (HU739_018780) | 4334293..4334718 | + | 426 | WP_186549690.1 | secondary thiamine-phosphate synthase enzyme YjbQ | - |
HU739_RS18785 (HU739_018785) | 4334821..4335147 | + | 327 | WP_186549688.1 | transcriptional regulator SutA | - |
HU739_RS18790 (HU739_018790) | 4335325..4336032 | - | 708 | WP_186549686.1 | HAD-IA family hydrolase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 93 a.a. Molecular weight: 10419.97 Da Isoelectric Point: 7.7181
>T206713 WP_186549755.1 NZ_CP077091:4331005-4331283 [Pseudomonas hamedanensis]
IMISFRCSETEYLFRSGKTRFWSAILSVAERKLTMLDAAAALADLRSPPGNRLETLGGDRKGQCSIRINAQWRICFVWGL
NGPEDVEIVDYH
IMISFRCSETEYLFRSGKTRFWSAILSVAERKLTMLDAAAALADLRSPPGNRLETLGGDRKGQCSIRINAQWRICFVWGL
NGPEDVEIVDYH
Download Length: 279 bp
>T206713 NZ_CP102665:327870-328307 [Sphingobium sp. JS3065]
GTGACCTATCTTCTCGACGTCAATGTGCTCGTTGCTCTGATCGATCCCAATCATGTCGGCCATGATGCCGCGCATCACTG
GTTCGAGTCCATCGGCGCCAGGGCCTGGGCGACGTGCCCCATCACCGAAAATGGGGTCATCCGCATCGTGGGGAACGTCA
AATATCCCTCGACCCCCGGTTCGCCAGCCGAGGTGGCGCGCATCATCGGGCAGATGCGGCAGTTGCCAGGGCACAGCTTC
TGGGCTGACGATATCAGCCTGCTGTCCGACGAGCGGGTCGACGAGAGCCGGCTTCTCACCTCTGCGCAGGTTACCGACAC
CTATCTCCTCGCGCTTGCCGTGGCGCATGATGGCAAGCTTGCCACCTTCGACCGGCGGCTCTCGCCCAGGGCCGTCAGCG
GCGGCAAGGCAGCCCTCCACCTCATCGGACATCAATGA
GTGACCTATCTTCTCGACGTCAATGTGCTCGTTGCTCTGATCGATCCCAATCATGTCGGCCATGATGCCGCGCATCACTG
GTTCGAGTCCATCGGCGCCAGGGCCTGGGCGACGTGCCCCATCACCGAAAATGGGGTCATCCGCATCGTGGGGAACGTCA
AATATCCCTCGACCCCCGGTTCGCCAGCCGAGGTGGCGCGCATCATCGGGCAGATGCGGCAGTTGCCAGGGCACAGCTTC
TGGGCTGACGATATCAGCCTGCTGTCCGACGAGCGGGTCGACGAGAGCCGGCTTCTCACCTCTGCGCAGGTTACCGACAC
CTATCTCCTCGCGCTTGCCGTGGCGCATGATGGCAAGCTTGCCACCTTCGACCGGCGGCTCTCGCCCAGGGCCGTCAGCG
GCGGCAAGGCAGCCCTCCACCTCATCGGACATCAATGA
Antitoxin
Download Length: 102 a.a. Molecular weight: 11287.02 Da Isoelectric Point: 6.4556
>AT206713 WP_186549696.1 NZ_CP077091:4331291-4331596 [Pseudomonas hamedanensis]
MTKNGMRPVHPGEILKEEYLEPLNLTAAALARALNVSTPTVNDIVLQRRGISADMALRLSICLDTTPEFWLNLQSTYDLR
KAEIERGAAIRDQVERLAHCA
MTKNGMRPVHPGEILKEEYLEPLNLTAAALARALNVSTPTVNDIVLQRRGISADMALRLSICLDTTPEFWLNLQSTYDLR
KAEIERGAAIRDQVERLAHCA
Download Length: 306 bp
>AT206713 NZ_CP102665:327649-327873 [Sphingobium sp. JS3065]
ATGCGTACGACACTGGTCATAGATGATGATGTGATGGAAGCCGCGCGCGCCATCGCGGAGCATCAGAACCGTTCGATCGG
CCAGGTCGTTTCCGATCTGGCCCGGCGCTCGCTGCGCGCCCCCGAAGCCGCACGCAGCCGCAACGGCATCGCCCTCCTCG
CCGCGAAACCCGGCGTCGTGGTGACGCCAGAGATCGTAAATGCGCTGCGAGACGAGGCGCCGTGA
ATGCGTACGACACTGGTCATAGATGATGATGTGATGGAAGCCGCGCGCGCCATCGCGGAGCATCAGAACCGTTCGATCGG
CCAGGTCGTTTCCGATCTGGCCCGGCGCTCGCTGCGCGCCCCCGAAGCCGCACGCAGCCGCAACGGCATCGCCCTCCTCG
CCGCGAAACCCGGCGTCGTGGTGACGCCAGAGATCGTAAATGCGCTGCGAGACGAGGCGCCGTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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