Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 5590922..5591577 Replicon chromosome
Accession NZ_CP077090
Organism Pseudomonas zeae strain OE 48.2

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag HU754_RS24595 Protein ID WP_127929688.1
Coordinates 5591233..5591577 (-) Length 115 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag HU754_RS24590 Protein ID WP_127929687.1
Coordinates 5590922..5591236 (-) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HU754_RS24570 (HU754_024570) 5586551..5587252 + 702 WP_110721302.1 hypothetical protein -
HU754_RS24575 (HU754_024575) 5587417..5588561 - 1145 Protein_4861 IS3 family transposase -
HU754_RS29530 5589032..5589505 + 474 WP_225919940.1 helix-turn-helix domain-containing protein -
HU754_RS29535 5589475..5589780 + 306 WP_225919941.1 hypothetical protein -
HU754_RS29540 5589765..5590151 + 387 WP_264082788.1 integrase core domain-containing protein -
HU754_RS24585 (HU754_024585) 5590230..5590721 - 492 WP_007916938.1 RidA family protein -
HU754_RS24590 (HU754_024590) 5590922..5591236 - 315 WP_127929687.1 helix-turn-helix domain-containing protein Antitoxin
HU754_RS24595 (HU754_024595) 5591233..5591577 - 345 WP_127929688.1 toxin Toxin
HU754_RS24600 (HU754_024600) 5591693..5592580 - 888 WP_007916939.1 heme o synthase -
HU754_RS24605 (HU754_024605) 5592592..5592927 - 336 WP_007916940.1 cytochrome o ubiquinol oxidase subunit IV -
HU754_RS24610 (HU754_024610) 5592927..5593550 - 624 WP_034156084.1 cytochrome o ubiquinol oxidase subunit III -
HU754_RS24615 (HU754_024615) 5593554..5595584 - 2031 WP_007916945.1 cytochrome o ubiquinol oxidase subunit I -
HU754_RS24620 (HU754_024620) 5595588..5596529 - 942 WP_007916947.1 ubiquinol oxidase subunit II -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 5588262..5588561 299


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(42-94)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 13341.23 Da        Isoelectric Point: 9.6212

>T206706 WP_127929688.1 NZ_CP077090:c5591577-5591233 [Pseudomonas zeae]
MRTVFFETTIFTTSVGQYLTDDEYRELQAYMQGNPLAGDVMPRTGGFRKLRWADARRGKGRRGGLRVIYYWLMNDGQFWM
FAIYDKDELENLTAEQEKALKKAIDKELKTRGTP

Download         Length: 345 bp

>T206706 NZ_CP102628:63943-64218 [Listeria innocua]
ATGAGTAAACATTTTCATGTGAGATTTGAAAAAGATGCTCAAAAAGTATTAAAAAAGATGGATCGATTTCAAGCGAAATT
GATTTTATCTTGGATTGAAAAGCATATCGAAGGATCAGATAATCCACGTCAACATGGTAAAAGCTTAGTTGGCAATCGTG
TAGGACAGTGGAGATATAGAGTAGGAGATTATCGCTTAATTGCAGAGATTCAAGATAATGAAGTGATAGTGTTAATTTTG
AACATCGGACACAGGAGAGATATTTACGATAAGTAA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11813.79 Da        Isoelectric Point: 10.2425

>AT206706 WP_127929687.1 NZ_CP077090:c5591236-5590922 [Pseudomonas zeae]
MKKRDLFAELMQGVDEMAAQREGKITLRNTVLEDKPVPEVGAQEIVALREKLHMSQAVFAKRIRASPSTLRNWEQEKSKP
NAQAALLIRLVEKFPDMVDRLSAV

Download         Length: 315 bp

>AT206706 NZ_CP102628:63725-63946 [Listeria innocua]
ATGACTACCATTACATTTCGAGTATCTGAACAAGAAAAGGCGTTTATTCAAGAAATGGCTAAGTTTAATGGTATATCTAT
TTCTGAACTCAGTCGCAAACAGATTATAGAAGGTTTAGAAGATCAAATTGATTTACAATCGTATGAGCGTGCTATAAAGG
CGCATCAGGTGAAAGATGAAAGTATTTCTTTTGATGAAATGAAAAAGGAACTTGATTTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References