Detailed information of TA system TA206704

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): higBA (relBE)/-
• Location: 2603984..2604638
• Replicon: chromosome
• Accession: NZ_CP077090
• Organism: Pseudomonas zeae strain OE 48.2

Toxin (Protein)

• Gene name: higB
• Uniprot ID: -
• Locus tag: HU754_RS11425
• Protein ID: WP_093434372.1
• Coordinates: 2604288..2604638 (-)
• Length: 117 a.a.

Antitoxin (Protein)

• Gene name: higA
• Uniprot ID: -
• Locus tag: HU754_RS11420
• Protein ID: WP_027614657.1
• Coordinates: 2603984..2604298 (-)
• Length: 105 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HU754_RS11400 (HU754_011400)	2600511..2600714	+	204	WP_186622550.1	co-regulatory protein PtrA N-terminal domain-containing protein	-
HU754_RS11405 (HU754_011405)	2600795..2601127	+	333	WP_186622548.1	DUF2790 domain-containing protein	-
HU754_RS11410 (HU754_011410)	2601538..2601918	+	381	WP_186622546.1	DUF6124 family protein	-
HU754_RS11415 (HU754_011415)	2602484..2603809	-	1326	WP_186622544.1	OprD family porin	-
HU754_RS11420 (HU754_011420)	2603984..2604298	-	315	WP_027614657.1	transcriptional regulator	Antitoxin
HU754_RS11425 (HU754_011425)	2604288..2604638	-	351	WP_093434372.1	toxin	Toxin
HU754_RS11430 (HU754_011430)	2605088..2606551	-	1464	WP_008082842.1	NADH-quinone oxidoreductase subunit NuoN	-
HU754_RS11435 (HU754_011435)	2606559..2608091	-	1533	WP_186622542.1	NADH-quinone oxidoreductase subunit M	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Cro/C1-type helix-turn-helix domain (41-100)

Sequences

Toxin

Protein

• Length: 117 a.a.
• Molecular weight: 13966.76 Da
• Isoelectric Point: 7.2021

>T206704 WP_093434372.1 NZ_CP077090:c2604638-2604288 [Pseudomonas zeae]
MDALFIELPVFQKHRDDYLDDDLFRSFQLELLKNPEAGDLIEDTGGLRKIRFGDQRRGKGKRSGLRVIYYWWSGFDQFWL
FTVYNKNEQDDLTPAQKKLFRKTLDRELNARTHYET

Nucleotide

• Length: 351 bp

>T206704 NZ_CP102626:660982-661329 [Listeria innocua]
CTGATGGTGAAGCGTGGTGACGTTTACTACGCGGACCTTTCCCCCGTGGTCGGAAGCGAGCAAGGGGGAATAAGGCCTGT
TCTCATCATTCAAAATGATATTGGTAATAGATTCAGTCCAACTGTGATCGTGGCAGCAATAACTGCAAAAATTCAAAAAG
CGAAGTTGCCAACACATGTGGAAGCTACTCGTAAAGACGGCTTTGAAAGAGATTCTGTCATTCTATTAGAACAAATTAGA
ACGATAGATAAACAACGCCTGACAGATAAGATTACACATTTGGACGAGGAACTAATGGCCAAGGTAAATCAGGCACTTGA
AGTCAGTCTAGGAGTAGTAGAATTTTAA

Antitoxin

Protein

• Length: 105 a.a.
• Molecular weight: 11950.86 Da
• Isoelectric Point: 9.9896

>AT206704 WP_027614657.1 NZ_CP077090:c2604298-2603984 [Pseudomonas zeae]
MKRDIFSELMDGLEALADERQGKITLRTHKVQLPKLMPITAEEVIAIRQQLNLSRSVFAMYLRTNTRTLENWEQGRATPN
AQATTLIRLVERFPQTIEQLAALT

Nucleotide

• Length: 315 bp

>AT206704 NZ_CP102626:660700-660978 [Listeria innocua]
GTGTTAGAGAAAGAAAAACGGACGATAATATCCGTAGAACTGACACAGGAAATGGTACAAGAACTCGACGTAGTTGTAGA
AAAAGAAAAAATGGGGCGGAGTGAAGTTATAATGGAAGCAACGCAACAATTTTTACAGGAGAAAAGAGCTCGTGAATTAA
GAGACGAGATGGAACGCGGCTATGCAGAAATGGCGACGATTAATTTCGCCATTGCGTGCGAGTGTACTCATGTCGAAGCA
GAGGCAGAAGACAGGAATATTAGTATTTTAGGAGGTTAA