Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 4200724..4201378 Replicon chromosome
Accession NZ_CP077087
Organism Pseudomonas monsensis strain PGSB 8459

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag HV782_RS18485 Protein ID WP_128614670.1
Coordinates 4200724..4201074 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag HV782_RS18490 Protein ID WP_123462457.1
Coordinates 4201064..4201378 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HV782_RS18475 (HV782_018480) 4197141..4198673 + 1533 WP_016986254.1 NADH-quinone oxidoreductase subunit M -
HV782_RS18480 (HV782_018485) 4198681..4200144 + 1464 WP_007920173.1 NADH-quinone oxidoreductase subunit NuoN -
HV782_RS18485 (HV782_018490) 4200724..4201074 + 351 WP_128614670.1 toxin Toxin
HV782_RS18490 (HV782_018495) 4201064..4201378 + 315 WP_123462457.1 transcriptional regulator Antitoxin
HV782_RS18495 (HV782_018500) 4201553..4202878 + 1326 WP_186744355.1 OprD family porin -
HV782_RS18500 (HV782_018505) 4203056..4204243 + 1188 WP_186744356.1 acyltransferase -
HV782_RS18505 (HV782_018510) 4204413..4204745 - 333 WP_123462451.1 DUF2790 domain-containing protein -
HV782_RS18510 (HV782_018515) 4204812..4205012 - 201 WP_186744357.1 co-regulatory protein PtrA N-terminal domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(46-100)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13907.73 Da        Isoelectric Point: 7.2019

>T206696 WP_128614670.1 NZ_CP077087:4200724-4201074 [Pseudomonas monsensis]
MDALFIELPVFQKHRDDYLDDDLFRSLQLELLKNPEAGDLIEDTGGLRKIRFSDQRRGKGKRSGLRVIYYWWSGFDQFWL
FTVYSKNEQDDLTPAQKKLFRKTLDKELNARTHYET

Download         Length: 351 bp

>T206696 NZ_CP102604:c369862-369401 [Pantoea sp. SOD02]
GTGATTTTCTATCGGCTAACCAAAACGCTATACGCTTCTGAAGCCTGGACCGGCAACGGTGCGAAACAGTATGGTGGCCG
CTGGAATCACAAAGGCCACCCAACCATTTATGTCGCGACCTCGGTTTCACTTGCCGCGCTTGAAGTGCTGGTGCACGTTT
CGAACGAGTCGATTTTGGATGAGTACACTTTATTCAGCATCGAGATTCCTGACGATGAAGTCTCCTACATTTCAGAAGAC
TTTTTGCCTGCTGACTGGCGCCAGGATCCGGCTCCAGTTTCAACTATGGATTTGGGCACAGGTTGGCTGCAATCGAGAGA
AGGTGCAGCGCTGATCATTCCTTCAAGCATTATTCCGATGGAAAATAATGCGATATTGAACCCGGAGCATCCGGTATTTG
AGAGTTATCTGTCGAGCGTAAATAAGTTACCGTTTGCATTCGATAAACGATTGATAAAATAA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11922.81 Da        Isoelectric Point: 9.9896

>AT206696 WP_123462457.1 NZ_CP077087:4201064-4201378 [Pseudomonas monsensis]
MKRDIFSELMDGLEALADERQGKITLRTHKVQLPKLMPITADEVVAIRQQLNLSRSVFAMYLRTNTRTLENWEQGRATPN
AQATTLIRLVERFPQTIEQLAALT

Download         Length: 315 bp

>AT206696 NZ_CP102604:c370302-369859 [Pantoea sp. SOD02]
ATGAGAGCCTACATTCCTGATGGCAAATCACATGACAATGCACTTTGGCGCTTTGCTGGCTTACCCCCACGCGGATTGGA
GCTAACTCGCATGCTTGAGGCGGGCTTGCCGGTCGCGGTGATTGATGACATTCGTCATTGGTCGGCAATGAGTAGAGCCG
AAATTATGAAGGTCACTGGCATCAATGAGCGAAATATTGCCCGCCGTAAAAGCGCAGGTAAAAGCTTGTCACCCGATGAG
AGCGAACGCATAGCCCGCTTCGTCCGAGTGATCGATGCAGCCGTTCAATTGTTTGGTGGTAATAAAGAAGATGCTACGCA
ATGGTTAAGCCGGCCGGTCAAAGGATTAGGCAACATTGCACCTATTACCTTGCTAGCCACTGAAAGCGGCGCACTGGATG
TGCTCGATTTGATTGGCCGTTTGGAGCATGGTGTCTTCTCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References