Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 1334234..1334889 Replicon chromosome
Accession NZ_CP077080
Organism Pseudomonas alvandae strain SWRI17

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag KSS97_RS05855 Protein ID WP_198796624.1
Coordinates 1334234..1334578 (+) Length 115 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID A0A923JRE9
Locus tag KSS97_RS05860 Protein ID WP_030139928.1
Coordinates 1334575..1334889 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KSS97_RS05830 (KSS97_05830) 1329250..1330197 + 948 WP_030139922.1 ubiquinol oxidase subunit II -
KSS97_RS05835 (KSS97_05835) 1330201..1332231 + 2031 WP_198796627.1 cytochrome o ubiquinol oxidase subunit I -
KSS97_RS05840 (KSS97_05840) 1332235..1332861 + 627 WP_053125033.1 cytochrome o ubiquinol oxidase subunit III -
KSS97_RS05845 (KSS97_05845) 1332862..1333197 + 336 WP_186705092.1 cytochrome o ubiquinol oxidase subunit IV -
KSS97_RS05850 (KSS97_05850) 1333209..1334096 + 888 WP_217861279.1 heme o synthase -
KSS97_RS05855 (KSS97_05855) 1334234..1334578 + 345 WP_198796624.1 toxin Toxin
KSS97_RS05860 (KSS97_05860) 1334575..1334889 + 315 WP_030139928.1 helix-turn-helix domain-containing protein Antitoxin
KSS97_RS05865 (KSS97_05865) 1335083..1335787 - 705 WP_217861280.1 hypothetical protein -
KSS97_RS05870 (KSS97_05870) 1335879..1336652 - 774 WP_217861281.1 DUF72 domain-containing protein -
KSS97_RS05875 (KSS97_05875) 1336729..1337742 - 1014 WP_217861282.1 sensor domain-containing diguanylate cyclase -
KSS97_RS05880 (KSS97_05880) 1337911..1338813 - 903 WP_217861283.1 LysR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(42-94)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 13790.73 Da        Isoelectric Point: 9.6383

>T206651 WP_198796624.1 NZ_CP077080:1334234-1334578 [Pseudomonas alvandae]
MRTLFFETTTFTATVGHYLTDDEYRLLQFYMQQHPEAGDVMPRTGGFRKLRWFDDRRGKGKRGGLRVIYYWLRHDRQFWM
FAIYDKDELENLTSEQEKTLKRAIEAELKVRGTL

Download         Length: 345 bp

>T206651 NZ_CP102546:3964173-3964541 [Klebsiella pneumoniae]
ATGACGCTGCAGATTATCTCAGCGGAAGAGATAATACAGTTTCACGACAGGCTGCTCCGCGTCACGCCTGGCGTTGCCGG
TATGCCCGATCCGGGGCGTGCCGAAGCGATAATGTATAGGGTGCTAAACAAAATTGAATATGAAGGTGTGACAGACGTGT
GGCGACTCGCTGCGATGCATCTGCTGGCGATTTCTCGCGGTCATATATTTAATGATGGTAATAAGCGTACGGCACTGTTT
ATCACCCTGCTTTTTTTAAAGCGAAATGGAATTATATTGCCAGCGAATCCAGACTTCGTCGGTATTACCGTCGAGGCAGC
AGCAGGGCAACTTACCCTGGAACAGATTGTCGCGCGTTTGCGTGGATGA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11799.77 Da        Isoelectric Point: 9.8896

>AT206651 WP_030139928.1 NZ_CP077080:1334575-1334889 [Pseudomonas alvandae]
MKKRDLFAEMMQGVEEMAAHREGKITLRQISIEDKPVPEVSAQEIVALRDRLHMSQAVFAKSIRTSPGTLRNWEQEKSKP
NAQAALLIKLVEKFPDMVERLGAV

Download         Length: 315 bp

>AT206651 NZ_CP102546:3963955-3964176 [Klebsiella pneumoniae]
ATGAGAACGGTTAACTATAGCGAAGCCCGGCAAAATCTGGCCGATGTGCTGGAAAGCGCAGTGACAGGTGTACCTGTGAC
CATTACCCGTCGTGGGCATAAATCTGCAGTCATCATTAGTGCAGAAGAGTTTGAACGCTACCAGGCGGCCAGAATGGATG
ATGAGTTCGCTGCTATCATGGCGGTTCATGGTGATGAGATCAGGGAGCTTGCGGATAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References