Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | higBA (relBE)/COG4683-HTH_37 |
Location | 5854961..5855624 | Replicon | chromosome |
Accession | NZ_CP077078 | ||
Organism | Pseudomonas azerbaijanoriens strain SWRI123 |
Toxin (Protein)
Gene name | higB | Uniprot ID | - |
Locus tag | KSS91_RS26340 | Protein ID | WP_102674224.1 |
Coordinates | 5855259..5855624 (-) | Length | 122 a.a. |
Antitoxin (Protein)
Gene name | higA | Uniprot ID | J3BKI2 |
Locus tag | KSS91_RS26335 | Protein ID | WP_008051594.1 |
Coordinates | 5854961..5855266 (-) | Length | 102 a.a. |
Genomic Context
Location: 5851048..5854794 (3747 bp)
Type: Others
Protein ID: WP_217836524.1
Type: Others
Protein ID: WP_217836524.1
Location: 5856203..5856523 (321 bp)
Type: Others
Protein ID: WP_217836525.1
Type: Others
Protein ID: WP_217836525.1
Location: 5856592..5857194 (603 bp)
Type: Others
Protein ID: WP_217836526.1
Type: Others
Protein ID: WP_217836526.1
Location: 5857184..5857612 (429 bp)
Type: Others
Protein ID: WP_217836527.1
Type: Others
Protein ID: WP_217836527.1
Location: 5854961..5855266 (306 bp)
Type: Antitoxin
Protein ID: WP_008051594.1
Type: Antitoxin
Protein ID: WP_008051594.1
Location: 5855259..5855624 (366 bp)
Type: Toxin
Protein ID: WP_102674224.1
Type: Toxin
Protein ID: WP_102674224.1
Location: 5857629..5858309 (681 bp)
Type: Others
Protein ID: WP_217838476.1
Type: Others
Protein ID: WP_217838476.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
KSS91_RS26325 (KSS91_26325) | 5851048..5854794 | + | 3747 | WP_217836524.1 | EAL domain-containing protein | - |
KSS91_RS26335 (KSS91_26335) | 5854961..5855266 | - | 306 | WP_008051594.1 | XRE family transcriptional regulator | Antitoxin |
KSS91_RS26340 (KSS91_26340) | 5855259..5855624 | - | 366 | WP_102674224.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
KSS91_RS26345 (KSS91_26345) | 5856203..5856523 | + | 321 | WP_217836525.1 | DUF3077 domain-containing protein | - |
KSS91_RS26350 (KSS91_26350) | 5856592..5857194 | + | 603 | WP_217836526.1 | nucleotidyltransferase domain-containing protein | - |
KSS91_RS26355 (KSS91_26355) | 5857184..5857612 | + | 429 | WP_217836527.1 | hypothetical protein | - |
KSS91_RS26360 (KSS91_26360) | 5857629..5858309 | - | 681 | WP_217838476.1 | peptidase M41 | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
No matching records found |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 122 a.a. Molecular weight: 14076.60 Da Isoelectric Point: 4.6964
>T206644 WP_102674224.1 NZ_CP077078:c5855624-5855259 [Pseudomonas azerbaijanoriens]
MKWDVEYTDEFEAWWDRLNEAEQDSVQATVMLLGEDGPHLGFPHTSDIKGSRHGNLRELRVQHAGRPYRVLYAFDPRRSA
ILLIGGDKTGQERWYAENVPLAERLYDEHLETLMKEGYDNG
MKWDVEYTDEFEAWWDRLNEAEQDSVQATVMLLGEDGPHLGFPHTSDIKGSRHGNLRELRVQHAGRPYRVLYAFDPRRSA
ILLIGGDKTGQERWYAENVPLAERLYDEHLETLMKEGYDNG
Download Length: 366 bp
>T206644 NZ_CP102546:219017-219119 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 102 a.a. Molecular weight: 11521.29 Da Isoelectric Point: 10.4463
>AT206644 WP_008051594.1 NZ_CP077078:c5855266-5854961 [Pseudomonas azerbaijanoriens]
MAKKFADLVARRSPESQARVEALHQKLRAQMPLHELRQAQALSQDTLARTLHVNQAAISKMERRTDMYISTLRNYIRAMG
GELEIIATFPEGQVKIENFAN
MAKKFADLVARRSPESQARVEALHQKLRAQMPLHELRQAQALSQDTLARTLHVNQAAISKMERRTDMYISTLRNYIRAMG
GELEIIATFPEGQVKIENFAN
Download Length: 306 bp
>AT206644 NZ_CP102546:c219126-218981 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
Structures
Toxin
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Source | ID | Structure |
---|---|---|
No matching records found |
Antitoxin
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Source | ID | Structure |
---|---|---|
AlphaFold DB | J3BKI2 |