Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 5854961..5855624 Replicon chromosome
Accession NZ_CP077078
Organism Pseudomonas azerbaijanoriens strain SWRI123

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag KSS91_RS26340 Protein ID WP_102674224.1
Coordinates 5855259..5855624 (-) Length 122 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID J3BKI2
Locus tag KSS91_RS26335 Protein ID WP_008051594.1
Coordinates 5854961..5855266 (-) Length 102 a.a.

Genomic Context


KSS91_RS26325KSS91_RS26345KSS91_RS26350KSS91_RS26355KSS91_RS26335KSS91_RS26340KSS91_RS26360
Location: 5851048..5854794 (3747 bp)
Type: Others
Protein ID: WP_217836524.1
Location: 5856203..5856523 (321 bp)
Type: Others
Protein ID: WP_217836525.1
Location: 5856592..5857194 (603 bp)
Type: Others
Protein ID: WP_217836526.1
Location: 5857184..5857612 (429 bp)
Type: Others
Protein ID: WP_217836527.1
Location: 5854961..5855266 (306 bp)
Type: Antitoxin
Protein ID: WP_008051594.1
Location: 5855259..5855624 (366 bp)
Type: Toxin
Protein ID: WP_102674224.1
Location: 5857629..5858309 (681 bp)
Type: Others
Protein ID: WP_217838476.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
KSS91_RS26325 (KSS91_26325)5851048..5854794+3747WP_217836524.1EAL domain-containing protein-
KSS91_RS26335 (KSS91_26335)5854961..5855266-306WP_008051594.1XRE family transcriptional regulatorAntitoxin
KSS91_RS26340 (KSS91_26340)5855259..5855624-366WP_102674224.1type II toxin-antitoxin system RelE/ParE family toxinToxin
KSS91_RS26345 (KSS91_26345)5856203..5856523+321WP_217836525.1DUF3077 domain-containing protein-
KSS91_RS26350 (KSS91_26350)5856592..5857194+603WP_217836526.1nucleotidyltransferase domain-containing protein-
KSS91_RS26355 (KSS91_26355)5857184..5857612+429WP_217836527.1hypothetical protein-
KSS91_RS26360 (KSS91_26360)5857629..5858309-681WP_217838476.1peptidase M41-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(13-106)

Antitoxin

(6-86)


Sequences


Toxin        


Download         Length: 122 a.a.        Molecular weight: 14076.60 Da        Isoelectric Point: 4.6964

>T206644 WP_102674224.1 NZ_CP077078:c5855624-5855259 [Pseudomonas azerbaijanoriens]
MKWDVEYTDEFEAWWDRLNEAEQDSVQATVMLLGEDGPHLGFPHTSDIKGSRHGNLRELRVQHAGRPYRVLYAFDPRRSA
ILLIGGDKTGQERWYAENVPLAERLYDEHLETLMKEGYDNG

Download         Length: 366 bp

>T206644 NZ_CP102546:219017-219119 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 11521.29 Da        Isoelectric Point: 10.4463

>AT206644 WP_008051594.1 NZ_CP077078:c5855266-5854961 [Pseudomonas azerbaijanoriens]
MAKKFADLVARRSPESQARVEALHQKLRAQMPLHELRQAQALSQDTLARTLHVNQAAISKMERRTDMYISTLRNYIRAMG
GELEIIATFPEGQVKIENFAN

Download         Length: 306 bp

>AT206644 NZ_CP102546:c219126-218981 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
AlphaFold DBJ3BKI2

References