Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 1014278..1015098 Replicon chromosome
Accession NZ_CP077077
Organism Pseudomonas maumuensis strain COW77

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag KSS90_RS04735 Protein ID WP_217868407.1
Coordinates 1014278..1014775 (-) Length 166 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID -
Locus tag KSS90_RS04740 Protein ID WP_110735832.1
Coordinates 1014772..1015098 (-) Length 109 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KSS90_RS04715 (KSS90_04715) 1009457..1010983 + 1527 WP_217868404.1 efflux transporter outer membrane subunit -
KSS90_RS04720 (KSS90_04720) 1010980..1013157 + 2178 WP_217868405.1 FUSC family protein -
KSS90_RS04725 (KSS90_04725) 1013162..1013362 + 201 WP_008097766.1 DUF1656 domain-containing protein -
KSS90_RS04730 (KSS90_04730) 1013373..1014233 + 861 WP_217868406.1 HlyD family secretion protein -
KSS90_RS04735 (KSS90_04735) 1014278..1014775 - 498 WP_217868407.1 type II toxin-antitoxin system YhaV family toxin Toxin
KSS90_RS04740 (KSS90_04740) 1014772..1015098 - 327 WP_110735832.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
KSS90_RS04745 (KSS90_04745) 1015208..1015654 - 447 WP_217868408.1 universal stress protein -
KSS90_RS04750 (KSS90_04750) 1015915..1016820 + 906 WP_046854222.1 LysR family transcriptional regulator -
KSS90_RS04755 (KSS90_04755) 1017086..1018627 + 1542 WP_217868409.1 MFS transporter -
KSS90_RS04760 (KSS90_04760) 1018655..1019716 + 1062 WP_217868410.1 HlyD family secretion protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(16-152)

Antitoxin

PrlF antitoxin

(8-106)


Sequences

Toxin        


Download         Length: 166 a.a.        Molecular weight: 19153.96 Da        Isoelectric Point: 10.3838

>T206640 WP_217868407.1 NZ_CP077077:c1014775-1014278 [Pseudomonas maumuensis]
MTETRRKPLCVHGWSVFAHPLFLDKLEALIDEVEVLKRKDPVGYVKKNAAKRLKAIRRLAFDVIAQAPGNPDHRMGGTLG
AEHKHWFRAKFFQQYRLFFRYHASSKIIVLAWVNDDDSKRAYESSDDAYRVFRRMLGNGHPPDDWDQLLQEATAATARFN
ATLKR

Download         Length: 498 bp

>T206640 NZ_CP102542:c513095-512910 [Lacticaseibacillus rhamnosus]
TTGCAGCGTCAAGGTCATGTAAAATTAGCTTCTCTACATGACCATGCTTTAAAGGGTGCTCACAGCGGCGAACGAGCATT
GCGTGTTGCTCCTGATTGGCTTCTCGTTTATAAAGTCGATGCTGAAGCGTTAATTTTAATGCTTCTTGCAACAGGCACAC
ACCGCGATACATTGAACATTGAGTAA

Antitoxin


Download         Length: 109 a.a.        Molecular weight: 12103.54 Da        Isoelectric Point: 4.2140

>AT206640 WP_110735832.1 NZ_CP077077:c1015098-1014772 [Pseudomonas maumuensis]
MATTFEAESTLTERYQTTVPETVRRALGLKKRDKIHYSIRPDGAVILTRAETAEEDPAVGQFLEFLERDIATNPQRLKVV
DAEFVARLDALVGDVEIDLDQPLSADDE

Download         Length: 327 bp

>AT206640 NZ_CP102542:c513395-513123 [Lacticaseibacillus rhamnosus]
ATGACCAAAAAATCCCGCATCAGCGTTAGGATTGATACCAAAACTAAAGAACGAGCGCTCCATGTTCTTAATAGCATGGG
ATTAGATATTTCCTCGGCTATTAACATGTACCTGAAACGGATTGGTGACACCGGTGCATTGCCATTTACACCTCCAATGT
CATTTGTTGATCAGCTTCAAGTTGCAGAAGCTGATGTTAAAGCGGGGCGAATAAAAAGCTTCAAGACTGTCGATGCTTTG
ATGAAGGATTTATACAGTGATGTTGACGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References