Detailed information of TA system TA206634

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): prlF-yhaV (relBE)/YhaV-PrlF
• Location: 1723836..1724656
• Replicon: chromosome
• Accession: NZ_CP077075
• Organism: Pseudomonas xanthosomae strain COR54

Toxin (Protein)

• Gene name: yhaV
• Uniprot ID: -
• Locus tag: KSS93_RS07680
• Protein ID: WP_225917314.1
• Coordinates: 1723836..1724288 (-)
• Length: 151 a.a.

Antitoxin (Protein)

• Gene name: prlF
• Uniprot ID: -
• Locus tag: KSS93_RS07685
• Protein ID: WP_217887782.1
• Coordinates: 1724330..1724656 (-)
• Length: 109 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KSS93_RS07655 (KSS93_07655)	1719279..1721456	+	2178	WP_217887777.1	FUSC family protein	-
KSS93_RS07660 (KSS93_07660)	1721446..1721646	+	201	WP_008097766.1	DUF1656 domain-containing protein	-
KSS93_RS07665 (KSS93_07665)	1721657..1722514	+	858	WP_217887778.1	HlyD family secretion protein	-
KSS93_RS07670 (KSS93_07670)	1722813..1723067	-	255	WP_217887779.1	DUF3077 domain-containing protein	-
KSS93_RS07675 (KSS93_07675)	1723084..1723317	-	234	WP_217887780.1	hypothetical protein	-
KSS93_RS07680 (KSS93_07680)	1723836..1724288	-	453	WP_225917314.1	type II toxin-antitoxin system YhaV family toxin	Toxin
KSS93_RS07685 (KSS93_07685)	1724330..1724656	-	327	WP_217887782.1	type II toxin-antitoxin system PrlF family antitoxin	Antitoxin
KSS93_RS07690 (KSS93_07690)	1724764..1725210	-	447	WP_217887783.1	universal stress protein	-
KSS93_RS07695 (KSS93_07695)	1725440..1726345	+	906	WP_217887784.1	LysR family transcriptional regulator	-
KSS93_RS07700 (KSS93_07700)	1726573..1728114	+	1542	WP_217887785.1	MFS transporter	-
KSS93_RS07705 (KSS93_07705)	1728143..1729204	+	1062	WP_217887786.1	HlyD family secretion protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	1722813..1731613	8800

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin endonuclease, YhaV (1-137)

Antitoxin

• PrlF antitoxin (8-106)

Sequences

Toxin

Protein

• Length: 151 a.a.
• Molecular weight: 17152.55 Da
• Isoelectric Point: 9.6236

>T206634 WP_225917314.1 NZ_CP077075:c1724288-1723836 [Pseudomonas xanthosomae]
VFAHPLFLDQLEALIDEVEALQKKDPVGYLRKNAAKRLGAIRRLAFDVIAQAPGSPVYRLGGTLGAEHKHWFRAKFFQQY
RLFFRYHASSKIIVLVWVNDDDCKRAYESSGDAYKVFRRMLGSGHPPDDWDQLLQEATAASDRLNSSLTR

Nucleotide

• Length: 453 bp

>T206634 NZ_CP102541:c1045521-1045237 [Bifidobacterium longum subsp. infantis]
ATGAGCACCGAATTCACCGACTACGACACCAGCGAATACCTCGAAAACGAACAGGACATCATCGCCTACCTCAACGCCAT
AGCCGAATATGACGACCCCGCACTCATGCAGGCCGCGCTCGGCAACGTCGCCAAGGCCCGGGGCATGACCCAGATCGCCA
AGGACGCGGGCGTGGGGCGCGAAAGCCTCTACAAGAGCCTCAGCAAGGACGGCAACCCCAGCTTCCAGACCATCGCCAAG
GTAATCCACGCCCTCGGCGGACGCCTCACCATCCAAGCCGCCTGA

Antitoxin

Protein

• Length: 109 a.a.
• Molecular weight: 11984.53 Da
• Isoelectric Point: 4.3668

>AT206634 WP_217887782.1 NZ_CP077075:c1724656-1724330 [Pseudomonas xanthosomae]
MATTFDVESTLTERYQTTVPETVRRALGLKKRDKIHYSIRPGGEVILTRAEATEDDPVVGQFMEFLARDIATNPQRLKVV
DAQLVARLDALVGGVDIDLDQPLSADDE

Nucleotide

• Length: 327 bp

>AT206634 NZ_CP102541:c1045820-1045518 [Bifidobacterium longum subsp. infantis]
ATCAAGCAATCCGCCGAATACCGCAAATGGTTCAAGAAACTCAGGGACCACAAAGCGAAGGCCGCCATCCAAGCCCGGCT
CGATGCCTGCAAGCTCGCAGGCAGGCCATTCGGCGACATCAAACCCGTGGGAGGCCCGGTCAGCGAGATGCGGTTCCACA
CCGGGGCCGGATACCGCGTCTACTTCGCCATGCAGGGCAACGTGCTCATGCTGCTGCTCGCAGGCGGCGACAAAAGCACC
CAGCAGACCGACATCAGACAAGCCCACGACATCCTCAACGACTACAAGGAACAACGACAATGA