Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 425705..426260 Replicon chromosome
Accession NZ_CP077075
Organism Pseudomonas xanthosomae strain COR54

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag KSS93_RS01825 Protein ID WP_217888665.1
Coordinates 425705..425962 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag KSS93_RS01830 Protein ID WP_217886921.1
Coordinates 425976..426260 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KSS93_RS01805 (KSS93_01805) 421120..422685 + 1566 WP_217886917.1 SulP family inorganic anion transporter -
KSS93_RS01810 (KSS93_01810) 422825..423649 - 825 WP_217886918.1 shikimate dehydrogenase -
KSS93_RS01815 (KSS93_01815) 423675..424586 - 912 WP_217886919.1 oxygen-dependent coproporphyrinogen oxidase -
KSS93_RS01820 (KSS93_01820) 424720..425697 + 978 WP_217886920.1 NADPH:quinone reductase -
KSS93_RS01825 (KSS93_01825) 425705..425962 - 258 WP_217888665.1 Txe/YoeB family addiction module toxin Toxin
KSS93_RS01830 (KSS93_01830) 425976..426260 - 285 WP_217886921.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
KSS93_RS01835 (KSS93_01835) 426543..427100 - 558 WP_217841101.1 L-threonylcarbamoyladenylate synthase -
KSS93_RS01840 (KSS93_01840) 427142..428239 - 1098 WP_217886922.1 DNA-processing protein DprA -
KSS93_RS01845 (KSS93_01845) 428448..428954 + 507 WP_038707094.1 peptide deformylase -
KSS93_RS01850 (KSS93_01850) 429014..429946 + 933 WP_217886923.1 methionyl-tRNA formyltransferase -
KSS93_RS01855 (KSS93_01855) 429943..431253 + 1311 WP_217886924.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10146.54 Da        Isoelectric Point: 7.2643

>T206633 WP_217888665.1 NZ_CP077075:c425962-425705 [Pseudomonas xanthosomae]
VRVAFTTQGWEDYHHWRESDPPIFEAINLLICECCRTPFRGIGKPEPLKGDLSGFWSRRITREHRLVYFYEGGQLTVLQC
RFHYD

Download         Length: 258 bp

>T206633 NZ_CP102541:c15161-14946 [Bifidobacterium longum subsp. infantis]
CTGGACGCCGGCCTTTTCAAACAGGTTGTATCCATTCTGTCCGAGGGCGGCACACTGCCCGACCGATATCATGACCATGC
GCTTACAGGCAATATGACCGGCTTCAGGGAGTGCCATATCACACCAGACCTGCTGTTGGTCTATCTCATAGAGAAGGACG
TGCTGGTGCTCACTCTGACCCGAACGGGCACCCATAGTGACCTTTTCGGAAAATAA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10663.05 Da        Isoelectric Point: 6.0752

>AT206633 WP_217886921.1 NZ_CP077075:c426260-425976 [Pseudomonas xanthosomae]
MHVLTFSQARADLKQTMDDVCRDHEPAIITRQRGEPVVMLSLEDYNGMQETLYLLGSSANAKRLRASIEQLRSGKPATHE
LKIDEHEVKATQQD

Download         Length: 285 bp

>AT206633 NZ_CP102541:c15511-15233 [Bifidobacterium longum subsp. infantis]
ATGAGCGGAACGACAACCACCGTCAACGTCCGAATGAACGCTGAGCTGAAAAAACAAGCCGAGGAACTGTTCGGGGAGCT
GGGCATGAACCTGACCACCGCAGTCAACATATTCATCCGCCAATCCCTGCGACAGGGCGGCATACCGTTCAACGTCTCGT
TGGATGAACCGAACAGGGAGACCGTCTCCGCCATGTTGGAGGCGAAGCGAATCGCAAGGGACGGGAACGTGAAAGGCTAC
CGGGACCTGAACGCCTTGTTCAAGGACTTGGACGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References