Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 2501654..2502355 Replicon chromosome
Accession NZ_CP077073
Organism Pseudomonas muyukensis strain COW39

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag KSS95_RS11225 Protein ID WP_217853714.1
Coordinates 2501654..2501950 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag KSS95_RS11230 Protein ID WP_217853715.1
Coordinates 2501954..2502355 (+) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KSS95_RS11205 (KSS95_11205) 2497649..2498827 - 1179 WP_217853711.1 efflux RND transporter periplasmic adaptor subunit -
KSS95_RS11210 (KSS95_11210) 2498980..2499522 + 543 WP_263974811.1 sigma-70 family RNA polymerase sigma factor -
KSS95_RS11215 (KSS95_11215) 2499691..2500176 + 486 WP_217853712.1 histidine kinase -
KSS95_RS11220 (KSS95_11220) 2500235..2501560 + 1326 WP_217853713.1 MFS transporter -
KSS95_RS11225 (KSS95_11225) 2501654..2501950 + 297 WP_217853714.1 type II toxin-antitoxin system MqsR family toxin Toxin
KSS95_RS11230 (KSS95_11230) 2501954..2502355 + 402 WP_217853715.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
KSS95_RS11235 (KSS95_11235) 2502580..2504244 - 1665 WP_217853716.1 electron transfer flavoprotein-ubiquinone oxidoreductase -
KSS95_RS11240 (KSS95_11240) 2504789..2505538 + 750 WP_134691771.1 electron transfer flavoprotein subunit beta/FixA family protein -
KSS95_RS11245 (KSS95_11245) 2505539..2506468 + 930 WP_217853717.1 FAD-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(5-97)

Antitoxin

Antitoxin MqsA/HigA-2

(1-131)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11003.85 Da        Isoelectric Point: 9.6270

>T206622 WP_217853714.1 NZ_CP077073:2501654-2501950 [Pseudomonas muyukensis]
MEKRTPHCSLARVHALLAEGLVRITHTAAKGAADLGISEEQLLAGVAQLTRGDFYKSMTSFADHRVWHDVYRPMTRVGRV
YLKLVVINDLLIVSFKEL

Download         Length: 297 bp

>T206622 NZ_CP102514:c4753013-4752750 [Streptomyces yangpuensis]
GTGAGTGAGTACCGAACCGTCTTCCGCCCCGAGGCGCAGGCTGAGCTTCGGAAGATCCCGCGCGAGATGGCACTGCGCAT
CCTGGCCAAGCTGACCGAGCTGGAAAGCGATCCGCTCGGCTTCAACACCACCGCACTCGTGTCCCAGCCAGACCGCCGGC
GACTACGGGTTGGCGACTACCGCGTCGTCTACACGATCGACAACGGGGAACTGGTGGTCTGGGTCGTTCACGTGGGGCAC
CGGTCCACCGTTTACGACACCTGA

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14811.21 Da        Isoelectric Point: 6.9075

>AT206622 WP_217853715.1 NZ_CP077073:2501954-2502355 [Pseudomonas muyukensis]
MKCPICGAGELVQAVRDLPYTYKGEAMVILQVEAEFCSACDEAIMTVPVARRVNAEMRAFNQRVNAMAVDPGFIATVRRK
FDLDQREAGEIFGGGVNAFSRYENGKTKPPLALIKLFKLLDRHPELFEEVKTA

Download         Length: 402 bp

>AT206622 NZ_CP102514:c4753275-4753006 [Streptomyces yangpuensis]
ATGACGCAGCCTCTACCCATAGAGTCCATCCGAGACGTGCGGGCACACCTCGCCGAGGTCGTGGAGCGCGCCGACCGCGA
CGACGTACCCACCGTGATCACGCGCCGCGGCAAGGAAGTCGCCGCCGTCGTCTCCATCGAGGTGCTGCGCAAGTACCAGG
AGTGGGAAGAGCGCGAGATCAATCGGATCATCGACGAGCGCATGGCCAACCCCGCACCCGGCATCCCGATCGAGGACATC
ATGAGGGAGACGCTGGCTCGCAGTGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References