Detailed information of TA system TA206554

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): TMCS/-
• Location: 2779481..2780060
• Replicon: chromosome
• Accession: NZ_CP076843
• Organism: Staphylococcus aureus strain 55-100-003

Toxin (Protein)

• Gene name: MW1434
• Uniprot ID: -
• Locus tag: KRH49_RS13465
• Protein ID: WP_103149612.1
• Coordinates: 2779481..2779726 (+)
• Length: 82 a.a.

Antitoxin (RNA)

Gene name	MW1433
Locus tag	-
Coordinates	2779695..2780060 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KRH49_RS13425 (KRH49_13425)	2775605..2776219	+	615	WP_000191459.1	hypothetical protein	-
KRH49_RS13430 (KRH49_13430)	2776216..2776362	-	147	WP_078067907.1	hypothetical protein	-
KRH49_RS13435 (KRH49_13435)	2776592..2777188	-	597	WP_031796639.1	hypothetical protein	-
KRH49_RS13440 (KRH49_13440)	2777245..2777874	-	630	WP_029549401.1	XRE family transcriptional regulator	-
KRH49_RS13445 (KRH49_13445)	2778028..2778255	+	228	WP_015978369.1	helix-turn-helix transcriptional regulator	-
KRH49_RS13450 (KRH49_13450)	2778278..2779054	+	777	WP_031796638.1	Rha family transcriptional regulator	-
KRH49_RS13455 (KRH49_13455)	2779083..2779226	+	144	WP_000939498.1	hypothetical protein	-
KRH49_RS13460 (KRH49_13460)	2779216..2779425	-	210	WP_000642492.1	hypothetical protein	-
KRH49_RS13465 (KRH49_13465)	2779481..2779726	+	246	WP_103149612.1	DUF2829 domain-containing protein	Toxin
KRH49_RS13470 (KRH49_13470)	2779695..2780060	-	366	WP_016170627.1	hypothetical protein	Antitoxin
KRH49_RS13475 (KRH49_13475)	2780115..2780330	+	216	WP_001097552.1	hypothetical protein	-
KRH49_RS13480 (KRH49_13480)	2780355..2780618	+	264	WP_016187436.1	helix-turn-helix domain-containing protein	-
KRH49_RS13485 (KRH49_13485)	2780631..2780792	+	162	WP_001285948.1	DUF1270 domain-containing protein	-
KRH49_RS13490 (KRH49_13490)	2780871..2781194	+	324	WP_000174994.1	hypothetical protein	-
KRH49_RS13495 (KRH49_13495)	2781209..2781571	+	363	WP_000985976.1	hypothetical protein	-
KRH49_RS13500 (KRH49_13500)	2781568..2782734	+	1167	WP_031794996.1	DUF2800 domain-containing protein	-
KRH49_RS13505 (KRH49_13505)	2782761..2783318	+	558	WP_000645049.1	DUF2815 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2774274..2796102	21828

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Protein of unknown function DUF2829 (2-69)

Sequences

Toxin

Protein

• Length: 82 a.a.
• Molecular weight: 9438.69 Da
• Isoelectric Point: 5.7783

>T206554 WP_103149612.1 NZ_CP076843:2779481-2779726 [Staphylococcus aureus]
MNIQEATKIATKNLVSMTRKDWKESHRTKILPTNDSFLQCIISNSDGANLIRYWQPSADDLMANDWEVINPTRDQELLKQ
F

Nucleotide

• Length: 246 bp

>T206554 NZ_CP102485:c244353-244060 [Burkholderia contaminans]
ATGAGAATCGAGCAGACAGACGACTTCGCGAAATGGTTGCGCGGCCTACGCGATCACATCGCGCGCGCGCAGATCGCCAA
GCGGATTCAACGGCTCGCGCGCGGCCAATATGGGGACATGAAGCCGGTGGGTGCCGGAGTGAGCGAAATGCGCGTGCACG
TCGGCCCCGGCTATCGCGTCTACTTTGTCCAACGAGGCTCAACGCTCGTCGTCCTGCTATGCGGTGGCGACAAGTCAACG
CAGCAGCGCGACATTGAGCGTGCTATCGCGCTTTCGGCGCAATTGGGAGATTGA

Antitoxin

Nucleotide

• Length: 366 bp

>AT206554 NZ_CP076843:c2780060-2779695 [Staphylococcus aureus]
ATGCCCTTGATATCTGATGAATTTGATACACTTACTAAAGACCAACAATATATCTTGTACGTACTCTACAAAGATTATTT
AGAATGTGTAAAGTTAGGTTCGGTTAAATTAACCTGCAATAATTTTGGAAGTGCTAAAGATATACATACAAAGTATTTTC
AAAAACTACATTTCGAAGATGTAAAATACGATTTAAATAAACTTAAAAACTCTGGGTTCCTAAACGGCGTGTATGCTAGT
AACACTATTTATCATGTAACAATTTCAGACAAGACTGTTGTTTACTTTGAAAATGAGTTTAAAAACAATTTAAAAAGTAT
CATTGATAGCATTTCTAAAATTGCTTCAATAATTCCTGGTCTCTAG

Structures

Antitoxin