Detailed information of TA system TA206552

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-SprA2AS/-
• Location: 2102944..2103128
• Replicon: chromosome
• Accession: NZ_CP076843
• Organism: Staphylococcus aureus strain 55-100-003

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: A0A2P7CQJ7
• Locus tag: KRH49_RS10400
• Protein ID: WP_000482647.1
• Coordinates: 2103021..2103128 (-)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprA2AS
Locus tag	-
Coordinates	2102944..2103004 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KRH49_RS10385 (KRH49_10385)	2098398..2098565	-	168	WP_001798790.1	hypothetical protein	-
KRH49_RS10390 (KRH49_10390)	2098796..2100529	-	1734	WP_000486511.1	ABC transporter ATP-binding protein	-
KRH49_RS10395 (KRH49_10395)	2100554..2102317	-	1764	WP_001064818.1	ABC transporter ATP-binding protein	-
-	2102944..2103004	+	61	-	-	Antitoxin
KRH49_RS10400 (KRH49_10400)	2103021..2103128	-	108	WP_000482647.1	type I toxin-antitoxin system Fst family toxin	Toxin
KRH49_RS10405 (KRH49_10405)	2103262..2103648	-	387	WP_000779355.1	flippase GtxA	-
KRH49_RS10410 (KRH49_10410)	2103915..2105057	+	1143	WP_001176859.1	glycerate kinase	-
KRH49_RS10415 (KRH49_10415)	2105117..2105776	+	660	WP_000831300.1	hypothetical protein	-
KRH49_RS10420 (KRH49_10420)	2105964..2107175	+	1212	WP_001191974.1	multidrug effflux MFS transporter	-
KRH49_RS10425 (KRH49_10425)	2107298..2107771	-	474	WP_000456489.1	GyrI-like domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 4012.76 Da
• Isoelectric Point: 10.4935

>T206552 WP_000482647.1 NZ_CP076843:c2103128-2103021 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Nucleotide

• Length: 108 bp

>T206552 NZ_CP102485:c166600-166190 [Burkholderia contaminans]
ATGACGCTGTACCTGCTCGATACCAACATTTTGTCGAACGTGATCCGCGACCCGCGCGGCGCATGCGCCACCCGGATTGG
AGAAACGCCGCCCGAACAAGTGTGCACCTCGATCATCGTGGCCGCGGAATTGCGGTTCGGCGTCTGGAAGCGTGGCTCGT
CAACGCTCGCGCAGCGCGTCGAGCAGCTGCTCGCAAGCCTGACCGTGTTGCCGCTGCAACCGGACGCGGACCGCTGCTAC
GGGCGGTTGCGGGCCGAGCTCGAGAAGCAAGGCCAGTTGATCGACGCCAACGACATGCTGATCGCCGCGCATGCGCTGGC
CGTCGACGCCGTGCTGGTCACGGACAACACGGCTGAATTCACCCGTATCGCGGGGCTGCCGGTCGAAAACTGGCTGCGGC
CGGCGACGTAA

Antitoxin

Nucleotide

• Length: 61 bp

>AT206552 NZ_CP076843:2102944-2103004 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Structures

Toxin

• AlphaFold DB: A0A2P7CQJ7

Antitoxin