Detailed information of TA system TA206551

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprG3-SprA2AS/-
• Location: 1806143..1806341
• Replicon: chromosome
• Accession: NZ_CP076843
• Organism: Staphylococcus aureus strain 55-100-003

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: Q2FWA7
• Locus tag: KRH49_RS08860
• Protein ID: WP_001802298.1
• Coordinates: 1806237..1806341 (-)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprA2AS
Locus tag	-
Coordinates	1806143..1806181 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KRH49_RS08840 (KRH49_08840)	1802263..1802928	-	666	WP_001024099.1	SDR family oxidoreductase	-
KRH49_RS08845 (KRH49_08845)	1803080..1803400	+	321	WP_000003759.1	Zn(II)-responsive metalloregulatory transcriptional repressor CzrA	-
KRH49_RS08850 (KRH49_08850)	1803402..1804382	+	981	WP_000019735.1	CDF family zinc efflux transporter CzrB	-
KRH49_RS08855 (KRH49_08855)	1804648..1805739	+	1092	WP_000495673.1	hypothetical protein	-
KRH49_RS13735	1806123..1806197	+	75	Protein_1709	hypothetical protein	-
-	1806143..1806181	+	39	-	-	Antitoxin
KRH49_RS08860 (KRH49_08860)	1806237..1806341	-	105	WP_001802298.1	hypothetical protein	Toxin
KRH49_RS08865 (KRH49_08865)	1807021..1807179	+	159	WP_001792784.1	hypothetical protein	-
KRH49_RS08870 (KRH49_08870)	1807615..1807707	+	93	WP_000220902.1	hypothetical protein	-
KRH49_RS08875 (KRH49_08875)	1807837..1808694	-	858	WP_000370942.1	HAD family hydrolase	-
KRH49_RS08880 (KRH49_08880)	1808762..1809544	-	783	WP_000908191.1	ABC transporter ATP-binding protein	-
KRH49_RS08885 (KRH49_08885)	1809834..1810442	-	609	WP_000101714.1	TIR domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3906.77 Da
• Isoelectric Point: 5.5724

>T206551 WP_001802298.1 NZ_CP076843:c1806341-1806237 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Nucleotide

• Length: 105 bp

>T206551 NZ_CP102483:2649677-2649976 [Burkholderia contaminans]
ATGGACAAGATCAGCACCCGGCCGTGGGATTCGGCCGATCATCTGAAAACCGAAGACGACATGGCCGACTACTTCGAAGC
GTGCCTGCAGGAAGCCGGCGACGATCCGGCTTTCATCGCGCATGCGCTCGGCGTGATCGCGCGTGCGCGCGGCATGTCGC
AGGTCGCGCGCGATGCGGGCCTGTCGCGCGAAGGGCTGTACAAGGCGCTGTCGCACGACGGCAACCCCAGCTTCGGCACG
ATCCTGAAGGTCATCAAGGCGCTCGGCCTGCAACTGCACGGCTCGAAAGCGCACGCATGA

Antitoxin

Nucleotide

• Length: 39 bp

>AT206551 NZ_CP076843:1806143-1806181 [Staphylococcus aureus]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC

Structures

Toxin

• AlphaFold DB: A0A2I7Y9L9

Antitoxin