Detailed information of TA system
Overview
TA module
| Type | I | Classification (family/domain) | sprG-sprF/- |
| Location | 2178849..2179112 | Replicon | chromosome |
| Accession | NZ_CP076839 | ||
| Organism | Staphylococcus aureus strain 55-100-016 | ||
Toxin (Protein)
| Gene name | SprG3 | Uniprot ID | Q2FWA7 |
| Locus tag | KRH48_RS10340 | Protein ID | WP_001802298.1 |
| Coordinates | 2178849..2178953 (+) | Length | 35 a.a. |
Antitoxin (RNA)
| Gene name | SprF2 | ||
| Locus tag | - | ||
| Coordinates | 2178948..2179112 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KRH48_RS10315 (KRH48_10315) | 2174748..2175356 | + | 609 | WP_000101714.1 | TIR domain-containing protein | - |
| KRH48_RS10320 (KRH48_10320) | 2175646..2176428 | + | 783 | WP_000908191.1 | ABC transporter ATP-binding protein | - |
| KRH48_RS10325 (KRH48_10325) | 2176496..2177353 | + | 858 | WP_000370942.1 | HAD family hydrolase | - |
| KRH48_RS10330 (KRH48_10330) | 2177483..2177575 | - | 93 | WP_000220902.1 | hypothetical protein | - |
| KRH48_RS10335 (KRH48_10335) | 2178011..2178169 | - | 159 | WP_001792784.1 | hypothetical protein | - |
| KRH48_RS10340 (KRH48_10340) | 2178849..2178953 | + | 105 | WP_001802298.1 | hypothetical protein | Toxin |
| - | 2178948..2179112 | - | 165 | - | - | Antitoxin |
| KRH48_RS10345 (KRH48_10345) | 2179385..2180476 | - | 1092 | WP_000495673.1 | hypothetical protein | - |
| KRH48_RS10350 (KRH48_10350) | 2180742..2181722 | - | 981 | WP_000019735.1 | CDF family zinc efflux transporter CzrB | - |
| KRH48_RS10355 (KRH48_10355) | 2181724..2182044 | - | 321 | WP_000003759.1 | Zn(II)-responsive metalloregulatory transcriptional repressor CzrA | - |
| KRH48_RS10360 (KRH48_10360) | 2182196..2182861 | + | 666 | WP_001024099.1 | SDR family oxidoreductase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 35 a.a. Molecular weight: 3906.77 Da Isoelectric Point: 5.5724
>T206534 WP_001802298.1 NZ_CP076839:2178849-2178953 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK
Download Length: 105 bp
>T206534 NZ_CP102479:c3332015-3331839 [Klebsiella aerogenes]
GTGAAGCAAAGCGAGTTGAGGCGTTGGCTTGCAGCTCAAGGGGCAGAGTTTAAAGATGGTACTAACCACCTGAAAATCTA
CCTCAACGGCAAGCAAACGGTAATGCCGAGACATCCGGGGAAGGAAATACCGGAACCGCTGAGGAAGGCAATTCTGAAGC
AACTTGGCATCAAATAA
GTGAAGCAAAGCGAGTTGAGGCGTTGGCTTGCAGCTCAAGGGGCAGAGTTTAAAGATGGTACTAACCACCTGAAAATCTA
CCTCAACGGCAAGCAAACGGTAATGCCGAGACATCCGGGGAAGGAAATACCGGAACCGCTGAGGAAGGCAATTCTGAAGC
AACTTGGCATCAAATAA
Antitoxin
Download Length: 165 bp
>AT206534 NZ_CP076839:c2179112-2178948 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
