Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2165811..2165995 Replicon chromosome
Accession NZ_CP076660
Organism Staphylococcus aureus strain SG511 Berlin

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag KQU62_RS10895 Protein ID WP_000482647.1
Coordinates 2165888..2165995 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2165811..2165871 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KQU62_RS10880 2161321..2161488 - 168 Protein_2107 hypothetical protein -
KQU62_RS10885 2161719..2163452 - 1734 WP_000486505.1 ABC transporter ATP-binding protein -
KQU62_RS10890 2163477..2165240 - 1764 WP_001064829.1 ABC transporter ATP-binding protein -
- 2165811..2165871 + 61 - - Antitoxin
KQU62_RS10895 2165888..2165995 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
KQU62_RS10900 2166129..2166515 - 387 WP_000779351.1 flippase GtxA -
KQU62_RS10905 2166783..2167925 + 1143 WP_001176855.1 glycerate kinase -
KQU62_RS10910 2167985..2168644 + 660 WP_000831298.1 membrane protein -
KQU62_RS10915 2168826..2170037 + 1212 WP_001191919.1 multidrug effflux MFS transporter -
KQU62_RS10920 2170160..2170633 - 474 WP_000456496.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T206180 WP_000482647.1 NZ_CP076660:c2165995-2165888 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T206180 NZ_CP076660:c2165995-2165888 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT206180 NZ_CP076660:2165811-2165871 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References