Detailed information of TA system TA206169

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1553200..1553380
• Replicon: chromosome
• Accession: NZ_CP076660
• Organism: Staphylococcus aureus strain SG511 Berlin

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: KQU62_RS07525
• Protein ID: WP_150860323.1
• Coordinates: 1553200..1553295 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1553323..1553380 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KQU62_RS07495	1548344..1548970	+	627	WP_000669038.1	hypothetical protein	-
KQU62_RS07500	1549011..1549355	+	345	WP_216701781.1	DUF3969 family protein	-
KQU62_RS07505	1549453..1550025	+	573	WP_216701782.1	hypothetical protein	-
KQU62_RS07510	1550174..1551541	-	1368	WP_216701783.1	FRG domain-containing protein	-
KQU62_RS07515	1551541..1552110	-	570	WP_000125075.1	ImmA/IrrE family metallo-endopeptidase	-
KQU62_RS07520	1552303..1552749	-	447	WP_000747804.1	DUF1433 domain-containing protein	-
KQU62_RS07525	1553200..1553295	+	96	WP_150860323.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	1553323..1553380	-	58	-	-	Antitoxin
KQU62_RS07530	1553418..1553519	+	102	WP_001791232.1	hypothetical protein	-
KQU62_RS07535	1553694..1554137	-	444	WP_001037039.1	DUF1433 domain-containing protein	-
KQU62_RS07540	1554137..1554580	-	444	WP_123089997.1	DUF1433 domain-containing protein	-
KQU62_RS07545	1554580..1555022	-	443	Protein_1490	DUF1433 domain-containing protein	-
KQU62_RS07550	1555547..1557967	+	2421	WP_033844720.1	polysaccharide lyase 8 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3582.37 Da
• Isoelectric Point: 10.4449

>T206169 WP_150860323.1 NZ_CP076660:1553200-1553295 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIVFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T206169 NZ_CP102179:c403106-402690 [Pseudomonas canavaninivorans]
ATGATCAAGTTCATGCTCGATACCAACATTTGTATTTTCACCATCAAGAACAAGCCCCAGGTCGTTAGAGAAGCGTTCAT
TCGTCATCACGGCCAGCTTTGCATCAGCGCCGTCACGCTTATGGAATTGATATACGGTGCAGAAAAATCATCCGCACCAG
AGAAAAACCTCAGCGTCATTGAAGGGTTCTGTGCACGACTTGAGGTCTTACCTTTTGGTTATGACGCTGCAGCACACACC
GGAATGATCCGGGCGGAATTGGCCAAAATAGGCAAACCAATCGGCCCCTACGACCAAATGATTGCCGGCCACGCCCGTTC
CCTCGGGCTGATCGTAGTCACCAATAATCTGAAAGAGTTTGAGAGAGTGCCCGGACTGCGTGTCGAGGATTGGACTCCCT
TGGCTTTAAAGCCTTGA

Antitoxin

Nucleotide

• Length: 58 bp

>AT206169 NZ_CP076660:c1553380-1553323 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin