Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 64892..65552 Replicon chromosome
Accession NZ_CP076651
Organism Serratia ureilytica strain S24

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag KQJ82_RS00310 Protein ID WP_089194950.1
Coordinates 65199..65552 (-) Length 118 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID A0A8G2G5Z5
Locus tag KQJ82_RS00305 Protein ID WP_016927038.1
Coordinates 64892..65194 (-) Length 101 a.a.

Genomic Context


KQJ82_RS00315KQJ82_RS00320KQJ82_RS00285KQJ82_RS00290KQJ82_RS00300KQJ82_RS00305KQJ82_RS00310KQJ82_RS00325KQJ82_RS00330
Location: 65991..67286 (1296 bp)
Type: Others
Protein ID: WP_196018657.1
Location: 67313..68119 (807 bp)
Type: Others
Protein ID: WP_033643757.1
Location: 60495..61409 (915 bp)
Type: Others
Protein ID: WP_033643752.1
Location: 61534..62652 (1119 bp)
Type: Others
Protein ID: WP_016927040.1
Location: 63258..64466 (1209 bp)
Type: Others
Protein ID: WP_123061821.1
Location: 64892..65194 (303 bp)
Type: Antitoxin
Protein ID: WP_016927038.1
Location: 65199..65552 (354 bp)
Type: Toxin
Protein ID: WP_089194950.1
Location: 68094..68993 (900 bp)
Type: Others
Protein ID: WP_033643758.1
Location: 69096..69461 (366 bp)
Type: Others
Protein ID: WP_033643759.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
KQJ82_RS00285 (KQJ82_00285)60495..61409-915WP_033643752.1branched-chain amino acid ABC transporter permease-
KQJ82_RS00290 (KQJ82_00290)61534..62652-1119WP_016927040.1branched-chain amino acid ABC transporter substrate-binding protein-
KQJ82_RS00300 (KQJ82_00300)63258..64466-1209WP_123061821.1aldose 1-epimerase family protein-
KQJ82_RS00305 (KQJ82_00305)64892..65194-303WP_016927038.1XRE family transcriptional regulatorAntitoxin
KQJ82_RS00310 (KQJ82_00310)65199..65552-354WP_089194950.1type II toxin-antitoxin system RelE/ParE family toxinToxin
KQJ82_RS00315 (KQJ82_00315)65991..67286+1296WP_196018657.1MFS transporter-
KQJ82_RS00320 (KQJ82_00320)67313..68119+807WP_033643757.1substrate-binding domain-containing protein-
KQJ82_RS00325 (KQJ82_00325)68094..68993-900WP_033643758.1LysR family transcriptional regulator-
KQJ82_RS00330 (KQJ82_00330)69096..69461-366WP_033643759.1diacylglycerol kinase-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(13-106)

Antitoxin

(12-89)


Sequences


Toxin        


Download         Length: 118 a.a.        Molecular weight: 13532.47 Da        Isoelectric Point: 9.0587

>T206115 WP_089194950.1 NZ_CP076651:c65552-65199 [Serratia ureilytica]
VWEIKTTDAFDHWFRSLSDADRAGVLAALMVLREKGPGLPRPYADTVKGSRYSNMKELRIQCRGEPLRAFFAFDPYRIGI
VLCAGNKAGNEKRFYDRMIQVADREFTNWLNTLNEKE

Download         Length: 354 bp

>T206115 NZ_CP102141:c2115836-2115507 [Streptococcus suis]
ATGGAATTTGAGTCATATTCAGTGATACTTGCTCCAGCAGTGGAGAGGGAATTGGCAGCTATTTACGCCTATTTCTCGGA
ACAGTTCTCAGAAGAAATTGCCAAAAGACGAATTGGGATGATTGTCCAAGCTTTGGAGAGTTTGCAAATTTTTCCTGAAC
GTGGCTTTAACGCCGATAACCGTTTTGGTAAGCAGATAGACCCGCCACATCTAACCCGAGGTTACGTTATTGGAAAAGAC
TACATCGCCCTCTATCGCGTAGTGAAAAATGAAGTTCGAGTGGGTCACCTTTTTGCGACCAAGAGTGATTATGTGAAGTT
GTTGAAGTGA

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 11093.96 Da        Isoelectric Point: 6.4738

>AT206115 WP_016927038.1 NZ_CP076651:c65194-64892 [Serratia ureilytica]
MGRTLEQLIADEKPEVVAKAQALAADIMLNIHLAELREKVQKTQVEMAQALGIRQPTVAVMEKPGRDLKLSSLKRYVEAA
GGKLRLDIELPDGSHYEFVL

Download         Length: 303 bp

>AT206115 NZ_CP102141:c2116113-2115826 [Streptococcus suis]
TTGATAACTATAAAGAAGGATGCCCAAGTAAATTTTAAAACTGATTCCAGACTTTTAGAAAAAGCCAAGGAAGTATTTGC
TATGAACCAGCTGGATTTGACTGCTGGTTTTAACCTCTTCTTGCAAAATATCGCTGTAAAAAATGAGTTGCCAATTCTGA
CTGAAGAAGAGTTGGAAAGAGAAGAGTTGTTTTTACAGCTTCAGAAGGAAATCCAGGAAAACCAACAGGCGATTGAGGCA
GGTCAAGGGATCAGCCTAGAAAGTGTCAAAGAGAAGTATGGAATTTGA

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
No matching records found

References