Detailed information of TA system TA020606

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1873356..1873538
• Replicon: chromosome
• Accession: NC_002953
• Organism: Staphylococcus aureus subsp. aureus MSSA476

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: SAS_RS15060
• Protein ID: WP_001801861.1
• Coordinates: 1873356..1873451 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1873479..1873538 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SAS_RS09155	1869026..1869652	+	627	WP_000669017.1	hypothetical protein	-
SAS_RS09160	1869693..1870034	+	342	WP_000627541.1	DUF3969 family protein	-
SAS_RS09165	1870135..1870707	+	573	WP_000414202.1	hypothetical protein	-
SAS_RS09170	1870905..1871462	-	558	Protein_1758	ImmA/IrrE family metallo-endopeptidase	-
SAS_RS09180	1871836..1872012	-	177	WP_000375477.1	hypothetical protein	-
SAS_RS09185	1872023..1872406	-	384	WP_000070814.1	hypothetical protein	-
SAS_RS09195	1873010..1873153	-	144	WP_001549059.1	transposase	-
SAS_RS15060	1873356..1873451	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1873479..1873538	-	60	-	-	Antitoxin
SAS_RS09200	1873574..1873675	+	102	WP_001791893.1	hypothetical protein	-
SAS_RS14715	1873653..1873829	-	177	Protein_1764	transposase	-
SAS_RS09205	1874023..1874400	-	378	Protein_1765	DUF1433 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T20606 WP_001801861.1 NC_002953:1873356-1873451 [Staphylococcus aureus subsp. aureus MSSA476]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T20606 NC_002953:1873356-1873451 [Staphylococcus aureus subsp. aureus MSSA476]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 60 bp

>AT20606 NC_002953:c1873538-1873479 [Staphylococcus aureus subsp. aureus MSSA476]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin