Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2596464..2596648 Replicon chromosome
Accession NC_002952
Organism Staphylococcus aureus subsp. aureus MRSA252

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag SAR_RS13205 Protein ID WP_000482647.1
Coordinates 2596541..2596648 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2596464..2596524 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SAR_RS13180 2591974..2592141 - 168 Protein_2503 hypothetical protein -
SAR_RS13190 2592372..2594105 - 1734 WP_000486505.1 ABC transporter ATP-binding protein/permease -
SAR_RS13195 2594130..2595893 - 1764 WP_001064829.1 ABC transporter ATP-binding protein/permease -
- 2596464..2596524 + 61 - - Antitoxin
SAR_RS13205 2596541..2596648 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
SAR_RS13210 2596782..2597168 - 387 WP_000779351.1 flippase GtxA -
SAR_RS13215 2597436..2598578 + 1143 WP_001176855.1 glycerate kinase -
SAR_RS13220 2598638..2599297 + 660 WP_000831298.1 membrane protein -
SAR_RS13225 2599479..2600690 + 1212 WP_001191919.1 multidrug effflux MFS transporter -
SAR_RS13230 2600813..2601286 - 474 WP_000456496.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T20603 WP_000482647.1 NC_002952:c2596648-2596541 [Staphylococcus aureus subsp. aureus MRSA252]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T20603 NC_002952:c2596648-2596541 [Staphylococcus aureus subsp. aureus MRSA252]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT20603 NC_002952:2596464-2596524 [Staphylococcus aureus subsp. aureus MRSA252]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References