Detailed information of TA system TA206002

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): hok-sok/-
• Location: 397665..397923
• Replicon: chromosome
• Accession: NZ_CP076594
• Organism: Erwinia amylovora isolate CP20086202

Toxin (Protein)

• Gene name: hok
• Uniprot ID: -
• Locus tag: KQH36_RS01790
• Protein ID: WP_231840709.1
• Coordinates: 397825..397923 (+)
• Length: 33 a.a.

Antitoxin (RNA)

Gene name	sok
Locus tag	-
Coordinates	397665..397711 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KQH36_RS01745 (KQH36_01725)	393111..393254	-	144	WP_004160049.1	hypothetical protein	-
KQH36_RS01750 (KQH36_01730)	393727..394119	-	393	WP_004160048.1	DoxX family protein	-
KQH36_RS01755 (KQH36_01735)	394329..394610	-	282	WP_004160039.1	YqjK-like family protein	-
KQH36_RS01760 (KQH36_01740)	394610..395002	-	393	WP_004160038.1	phage holin family protein	-
KQH36_RS01765 (KQH36_01745)	395004..395309	-	306	WP_004160037.1	DUF883 family protein	-
KQH36_RS01770 (KQH36_01750)	395352..395723	-	372	WP_004160036.1	DUF1090 domain-containing protein	-
KQH36_RS01775 (KQH36_01755)	395891..396283	-	393	WP_004160035.1	EnvZ/OmpR regulon moderator MzrA	-
KQH36_RS01780 (KQH36_01760)	396280..396954	-	675	WP_004160034.1	DedA family protein	-
-	397665..397711	-	47	-	-	Antitoxin
KQH36_RS01790	397825..397923	+	99	WP_231840709.1	Hok/Gef family protein	Toxin
KQH36_RS01795 (KQH36_01770)	398067..399299	-	1233	WP_004160030.1	serine/threonine transporter SstT	-
KQH36_RS01800 (KQH36_01775)	399534..400514	-	981	WP_013035818.1	TerC family protein	-
KQH36_RS01805 (KQH36_01780)	400927..402618	+	1692	WP_004160025.1	chloride channel protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Hok/gef cell toxic protein (2-28)

Sequences

Toxin

Protein

• Length: 33 a.a.
• Molecular weight: 3810.40 Da
• Isoelectric Point: 8.9407

>T206002 WP_231840709.1 NZ_CP076594:397825-397923 [Erwinia amylovora]
IFTYLTRKSLCEIRYKDGYREVAAFMAYESGK

Nucleotide

• Length: 99 bp

>T206002 NZ_CP102061:3625969-3626256 [Escherichia coli]
ATGCCAATGGAGTTTGAATGGGATGCAAACAAGGCCAAAAGTAATCGGGTGAAACATGGCATCCGCTTTGAAGATGCGGT
GTTAGTGTTTGATGATCCACAACATTTGTCACAGCAAGATCGCATAGAAAACGGTGAGTATCGCTGGCAGACTATCGGCC
TGGTTCACGGTATCGTGGTTATTCTGGTTGCGCATACCATCCGTTTCGAAAGCGGAAATGAAATTATTCGAATCATCAGT
GCACGAAAAGCAGATCGTAAAGAGAGGAGCCGCTATGAGCATGGTTAA

Antitoxin

Nucleotide

• Length: 47 bp

>AT206002 NZ_CP076594:c397711-397665 [Erwinia amylovora]
GCATGCAGATGGCCTCGTGGATTAATGAAAATTAACTACGGGGCTTT

Structures

Antitoxin