Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2305998..2306214 Replicon chromosome
Accession NC_002952
Organism Staphylococcus aureus subsp. aureus MRSA252

Toxin (Protein)


Gene name SprG3 Uniprot ID -
Locus tag SAR_RS11665 Protein ID WP_073392962.1
Coordinates 2306110..2306214 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2305998..2306053 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SAR_RS11645 2301090..2301410 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
SAR_RS11650 2301412..2302392 + 981 WP_000019741.1 CDF family zinc efflux transporter CzrB -
SAR_RS11655 2302658..2303749 + 1092 WP_000495684.1 hypothetical protein -
SAR_RS11660 2304037..2305684 + 1648 Protein_2213 IS1182-like element ISSau3 family transposase -
- 2305998..2306053 + 56 - - Antitoxin
SAR_RS11665 2306110..2306214 - 105 WP_073392962.1 hypothetical protein Toxin
SAR_RS15385 2306894..2307052 + 159 WP_001792784.1 hypothetical protein -
SAR_RS11670 2307711..2308568 - 858 WP_000370937.1 Cof-type HAD-IIB family hydrolase -
SAR_RS11675 2308636..2309418 - 783 WP_000908186.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3920.80 Da        Isoelectric Point: 5.5724

>T20600 WP_073392962.1 NC_002952:c2306214-2306110 [Staphylococcus aureus subsp. aureus MRSA252]
MLLLERTSMSDFEMLMIVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T20600 NC_002952:c2306214-2306110 [Staphylococcus aureus subsp. aureus MRSA252]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGATTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT20600 NC_002952:2305998-2306053 [Staphylococcus aureus subsp. aureus MRSA252]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References