Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) hok-sok/-
Location 2966397..2966655 Replicon chromosome
Accession NZ_CP076590
Organism Erwinia amylovora isolate CP200930

Toxin (Protein)


Gene name hok Uniprot ID D4I1C1
Locus tag KQH39_RS13620 Protein ID WP_004160031.1
Coordinates 2966397..2966555 (-) Length 53 a.a.

Antitoxin (RNA)


Gene name sok
Locus tag -
Coordinates 2966609..2966655 (+)

Genomic Context


KQH39_RS13610KQH39_RS13615--KQH39_RS13625KQH39_RS13630KQH39_RS13635KQH39_RS13640KQH39_RS13645KQH39_RS13650KQH39_RS13655KQH39_RS13660KQH39_RS13605KQH39_RS13620
Location: 2963806..2964786 (981 bp)
Type: Others
Protein ID: WP_013035818.1
Location: 2965021..2966253 (1233 bp)
Type: Others
Protein ID: WP_004160030.1
Location: 2966609..2966655 (47 bp)
Type: Antitoxin
Protein ID: -
Location: 2967366..2968040 (675 bp)
Type: Others
Protein ID: WP_004160034.1
Location: 2968037..2968429 (393 bp)
Type: Others
Protein ID: WP_004160035.1
Location: 2968597..2968968 (372 bp)
Type: Others
Protein ID: WP_004160036.1
Location: 2969011..2969316 (306 bp)
Type: Others
Protein ID: WP_004160037.1
Location: 2969318..2969710 (393 bp)
Type: Others
Protein ID: WP_004160038.1
Location: 2969710..2969991 (282 bp)
Type: Others
Protein ID: WP_004160039.1
Location: 2970201..2970593 (393 bp)
Type: Others
Protein ID: WP_004160048.1
Location: 2971066..2971209 (144 bp)
Type: Others
Protein ID: WP_004160049.1
Location: 2961702..2963393 (1692 bp)
Type: Others
Protein ID: WP_004160025.1
Location: 2966397..2966555 (159 bp)
Type: Toxin
Protein ID: WP_004160031.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
KQH39_RS13605 (KQH39_13645)2961702..2963393-1692WP_004160025.1chloride channel protein-
KQH39_RS13610 (KQH39_13650)2963806..2964786+981WP_013035818.1TerC family protein-
KQH39_RS13615 (KQH39_13655)2965021..2966253+1233WP_004160030.1serine/threonine transporter SstT-
KQH39_RS13620 (KQH39_13660)2966397..2966555-159WP_004160031.1type I toxin-antitoxin system Hok family toxinToxin
-2966609..2966655+47--Antitoxin
KQH39_RS13625 (KQH39_13665)2967366..2968040+675WP_004160034.1DedA family protein-
KQH39_RS13630 (KQH39_13670)2968037..2968429+393WP_004160035.1EnvZ/OmpR regulon moderator MzrA-
KQH39_RS13635 (KQH39_13675)2968597..2968968+372WP_004160036.1DUF1090 domain-containing protein-
KQH39_RS13640 (KQH39_13680)2969011..2969316+306WP_004160037.1DUF883 family protein-
KQH39_RS13645 (KQH39_13685)2969318..2969710+393WP_004160038.1phage holin family protein-
KQH39_RS13650 (KQH39_13690)2969710..2969991+282WP_004160039.1YqjK-like family protein-
KQH39_RS13655 (KQH39_13695)2970201..2970593+393WP_004160048.1DoxX family protein-
KQH39_RS13660 (KQH39_13700)2971066..2971209+144WP_004160049.1hypothetical protein-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(8-48)


Sequences


Toxin        


Download         Length: 53 a.a.        Molecular weight: 6038.32 Da        Isoelectric Point: 8.4901

>T205979 WP_004160031.1 NZ_CP076590:c2966555-2966397 [Erwinia amylovora]
MKLPANCLIWCVLIVCVTLLIFTYLTRKSLCEIRYKDGYREVAAFMAYESGK

Download         Length: 159 bp

>T205979 NZ_CP101986:165647-165979 [Streptococcus mutans]
GTGGTAACCATCAAGCAAGGGTCAATTATCAAAATTAACTTGGATCCCAAACAAGGACATGAACAAAAAGGGTATCGTCC
GTACATTTGTCTAAACCATAGTATCGTAACCAAGTATTCTAATATTGCTATTTTTGCGCCAATTAGCAATACCAAGCGTG
ATTACCCTTTTTATGTTCCCCTAGAAGGAACAGAATCCACAGGGAAAGTATTATTAGACCAACTGGTTACAATCGATTTT
AATGCTAGAGATTATCGTTATGTGGAGGATATTCAGGAAGACTTATTAGATGAACTTTTAGCTAGGGTCAAGGTGCTATT
TGAAAAAGGATAA

Antitoxin


Download         Length: 47 bp

>AT205979 NZ_CP076590:2966609-2966655 [Erwinia amylovora]
GCATGCAGATGGCCTCGTGGATTAATGAAAATTAACTACGGGGCTTT

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
AlphaFold DBA0A831A7I1


Antitoxin

Download structure file

References