Detailed information of TA system TA205959

Bioinformatically predicted

Overview

TA module

• Type: III
• Classification (family/domain): cptIN/-
• Location: 65916..66497
• Replicon: chromosome
• Accession: NZ_CP076562
• Organism: Eubacterium sp. MSJ-33

Toxin (Protein)

• Gene name: cptN
• Uniprot ID: -
• Locus tag: KP625_RS00280
• Protein ID: WP_238298553.1
• Coordinates: 66003..66497 (+)
• Length: 165 a.a.

Antitoxin (RNA)

Gene name	cptI
Locus tag	-
Coordinates	65916..65961 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KP625_RS00250 (61402)	61402..62214	+	813	WP_238298540.1	zinc dependent phospholipase C family protein	-
KP625_RS00255 (62165)	62165..63499	+	1335	WP_238298543.1	MFS transporter	-
KP625_RS00260 (63651)	63651..63932	+	282	WP_238298545.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	-
KP625_RS00265 (63922)	63922..64236	+	315	WP_238298547.1	type II toxin-antitoxin system RelE/ParE family toxin	-
KP625_RS00270 (64254)	64254..64421	+	168	WP_238298549.1	hypothetical protein	-
KP625_RS00275 (64432)	64432..65328	+	897	WP_238298550.1	hypothetical protein	-
- (65916)	65916..65961	+	46	NuclAT_0	-	Antitoxin
- (65916)	65916..65961	+	46	NuclAT_0	-	Antitoxin
- (65916)	65916..65961	+	46	NuclAT_0	-	Antitoxin
KP625_RS00280 (66003)	66003..66497	+	495	WP_238298553.1	hypothetical protein	Toxin
KP625_RS00285 (66510)	66510..66680	+	171	WP_238298555.1	integrase	-
KP625_RS00290 (66871)	66871..67791	+	921	WP_238298557.1	DUF4268 domain-containing protein	-
KP625_RS00295 (67805)	67805..68509	+	705	WP_238298559.1	hypothetical protein	-
KP625_RS00300 (68734)	68734..69231	+	498	WP_238298561.1	low molecular weight protein-tyrosine-phosphatase	-
KP625_RS00305 (69609)	69609..70988	+	1380	WP_238298563.1	PhoH family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 165 a.a.
• Molecular weight: 19296.30 Da
• Isoelectric Point: 7.7835

>T205959 WP_238298553.1 NZ_CP076562:66003-66497 [Eubacterium sp. MSJ-33]
MTVGEEMEIGHFYYINDQYFKDFPDSYLMQNKEKVNGQLHDRPCFYAFQDSNTQLFWMIPFSSQTSKFKGIYNKKMQKYH
RCDTIVFGEVLGHEKAFLIQNMCPITEKYMKNEYLDSVANIPVRVDGRLEKELKDKAGKVLALQRKGAKLIFPDVLSIEQ
ELLK

Nucleotide

• Length: 495 bp

>T205959 NZ_CP101940:c2569339-2568848 [Salmonella enterica subsp. enterica]
ATGATCTCCTCCCCTGAGCCGCTTCATGCCGGACATATTCTTACTCCGTTTTGCTGCGGTGTGGATTCTATGGATAACTG
GCTGAAACAGCGGGCGATGAAAAATCAGACCACTGGTGCGTCCCGTACCTTTGTGTGTTGTGGCAGCGATTCGAACGTAC
TGGCCTATTACTCGCTGGCGTCCAGCGCGGTCACGACGAATACCGCCCCCGGTCGCTTTCGTCGCAATATGCCTGACCCG
ATCCCGATTGTGGTATTGGGGCGTCTGGCGGTGGATAAATCGCTTCATGGGCAGGGCGTTGGTCGGGCGCTGGTACGCGA
CGCAGGGCTGCGGGTTATTCAGGTGGCGGAGACTATCGGCATTCGCGGGATGCTGGTTCACGCCCTGTCGGATGAAGCGC
GGGAATTTTACCAGCGGGTGGGGTTTGAACCATCGCCGATGGATCCGATGATGTTGATGGTGACGTTGGGGGATTTGGTG
GAGAGTGTTTAA

Antitoxin

Nucleotide

• Length: 46 bp

>AT205959 NZ_CP076562:65916-65961 [Eubacterium sp. MSJ-33]
CAAATGTTTGTCGCTACTCGATATGCGACTTAGAAAAGGTCGAGTT

Structures

Antitoxin