Detailed information of TA system TA205878

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/Fst(toxin)
• Location: 41164..41378
• Replicon: plasmid pUAMSEL2
• Accession: NZ_CP076500
• Organism: Enterococcus faecalis strain UAMS_EL53

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: KPU58_RS15890
• Protein ID: WP_002360667.1
• Coordinates: 41164..41274 (+)
• Length: 37 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	41314..41378 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KPU58_RS15845	36240..36497	+	258	WP_010824092.1	hypothetical protein	-
KPU58_RS15850	36494..36832	+	339	WP_049098551.1	type II toxin-antitoxin system PemK/MazF family toxin	-
KPU58_RS15855	37037..37654	+	618	WP_025191668.1	recombinase family protein	-
KPU58_RS15860	37695..37994	+	300	WP_142657760.1	BRCT domain-containing protein	-
KPU58_RS15865	38028..38225	+	198	WP_048669782.1	hypothetical protein	-
KPU58_RS15870	38493..38810	+	318	WP_224813313.1	DUF6440 family protein	-
KPU58_RS15875	39238..40566	+	1329	WP_002400994.1	ultraviolet resistance protein UvrA	-
KPU58_RS15880	40563..40913	+	351	WP_002400993.1	hypothetical protein	-
KPU58_RS15885	40870..41082	+	213	WP_002360669.1	hypothetical protein	-
KPU58_RS15890	41164..41274	+	111	WP_002360667.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	41314..41378	-	65	-	-	Antitoxin
KPU58_RS15895	41546..41809	+	264	WP_082148692.1	type III secretion system protein PrgN	-
KPU58_RS15900	41976..42317	-	342	WP_002382053.1	hypothetical protein	-
KPU58_RS15905	42321..43223	-	903	WP_002382055.1	AAA family ATPase	-
KPU58_RS15910	43619..44620	+	1002	WP_142657759.1	replication initiator protein A	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	EF0149	1..55301	55301

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 37 a.a.
• Molecular weight: 4117.92 Da
• Isoelectric Point: 4.1672

>T205878 WP_002360667.1 NZ_CP076500:41164-41274 [Enterococcus faecalis]
VLFVKDLMSLVIAPIFVGLVLEMISRVLDEEDDNRK

Nucleotide

• Length: 111 bp

>T205878 NZ_CP101921:c1874654-1874277 [Escherichia coli]
ATGAAAACATTACCCGATACACACGTACGGGAGGCATCGAGCTGCCCGTCCCCCGTCACCATCTGGCAGACTCTGCTCTC
CCGACTACTGGGCCAGCATTACGGCCTTACACTGAATGACACACCGTTCGCCGATGAACGTGTGATTGAGCAGCATATTG
AAGCTGGCATTTCACTGTGTGATGCGGTGAATTTTCTCGTGGAAAAATACGCGCTGGTGCGTACCGACCAGCCGGGATTC
AGCACTTGTCCCCGCTCTCAGTTAATAAACAGTATTGATATCCTCCGGGCTCGCCGGGCAACAGGCCTGATGACCCGCGA
CAATTACAGAACGGTAAATAACATTACCCTGGGGAAGCATCCGGAGGCGAAACGATGA

Antitoxin

Nucleotide

• Length: 65 bp

>AT205878 NZ_CP076500:c41378-41314 [Enterococcus faecalis]
AACGACATTAAATCGTACAAATAACACAAAAAGCAATCCTACGGCGAATAGGATTGCTTTTTTTT

Structures

Antitoxin