Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) fst-RNAII/Fst(toxin)
Location 2504..2718 Replicon plasmid pUAMSEL1
Accession NZ_CP076499
Organism Enterococcus faecalis strain UAMS_EL53

Toxin (Protein)


Gene name fst Uniprot ID -
Locus tag KPU58_RS14935 Protein ID WP_002360667.1
Coordinates 2504..2614 (+) Length 37 a.a.

Antitoxin (RNA)


Gene name RNAII
Locus tag -
Coordinates 2654..2718 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KPU58_RS14920 578..1906 + 1329 WP_129268066.1 ultraviolet resistance protein UvrA -
KPU58_RS14925 1903..2253 + 351 WP_002360672.1 hypothetical protein -
KPU58_RS14930 2210..2422 + 213 Protein_3 excinuclease ABC subunit C -
KPU58_RS14935 2504..2614 + 111 WP_002360667.1 type I toxin-antitoxin system Fst family toxin Toxin
- 2654..2718 - 65 - - Antitoxin
KPU58_RS14940 2854..3144 + 291 WP_001137528.1 hypothetical protein -
KPU58_RS14945 3248..3619 - 372 WP_000049959.1 replication-associated protein RepC -
KPU58_RS14950 3612..4457 - 846 WP_000239313.1 AAA family ATPase -
KPU58_RS14955 4929..5939 + 1011 WP_001058676.1 replication initiator protein A -
KPU58_RS14960 5983..6966 + 984 WP_000007382.1 prolipoprotein diacylglyceryl transferase -
KPU58_RS14965 6891..7079 + 189 Protein_10 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid erm(B) / ant(6)-Ia / aph(3')-III cylR2 / cylR1 / cylL / cylS / cylM / cylB / cylA / cylI 1..119720 119720


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(1-35)


Sequences


Toxin        


Download         Length: 37 a.a.        Molecular weight: 4117.92 Da        Isoelectric Point: 4.1672

>T205870 WP_002360667.1 NZ_CP076499:2504-2614 [Enterococcus faecalis]
VLFVKDLMSLVIAPIFVGLVLEMISRVLDEEDDNRK

Download         Length: 111 bp

>T205870 NZ_CP101921:199721-199828 [Escherichia coli]
ATGACGCTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAACGGAAGTAA

Antitoxin


Download         Length: 65 bp

>AT205870 NZ_CP076499:c2718-2654 [Enterococcus faecalis]
AACGACATTAAATCGTACAAATAACACAAAAAGCAATCCTACGGCGAATAGGATTGCTTTTTTTT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References