Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | fst-RNAII/- |
Location | 72137..72331 | Replicon | chromosome |
Accession | NZ_CP076498 | ||
Organism | Enterococcus faecalis strain UAMS_EL53 |
Toxin (Protein)
Gene name | fst | Uniprot ID | - |
Locus tag | KPU58_RS00355 | Protein ID | WP_015543884.1 |
Coordinates | 72137..72232 (+) | Length | 32 a.a. |
Antitoxin (RNA)
Gene name | RNAII | ||
Locus tag | - | ||
Coordinates | 72267..72331 (-) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
KPU58_RS00335 | 67316..68431 | + | 1116 | WP_002379062.1 | FAD-dependent oxidoreductase | - |
KPU58_RS00340 | 68498..69652 | - | 1155 | WP_002355280.1 | mannitol-1-phosphate 5-dehydrogenase | - |
KPU58_RS00345 | 69667..70104 | - | 438 | WP_002355279.1 | PTS sugar transporter subunit IIA | - |
KPU58_RS00350 | 70119..71891 | - | 1773 | WP_010706745.1 | PTS mannitol-specific transporter subunit IIBC | - |
KPU58_RS00355 | 72137..72232 | + | 96 | WP_015543884.1 | type I toxin-antitoxin system Fst family toxin | Toxin |
- | 72267..72331 | - | 65 | - | - | Antitoxin |
KPU58_RS00360 | 72487..72921 | - | 435 | WP_002358391.1 | PTS sugar transporter subunit IIA | - |
KPU58_RS00365 | 72932..74965 | - | 2034 | WP_002387671.1 | PRD domain-containing protein | - |
KPU58_RS00370 | 74956..76698 | - | 1743 | WP_002399652.1 | PTS transporter subunit EIIC | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 32 a.a. Molecular weight: 3659.47 Da Isoelectric Point: 4.6275
>T205842 WP_015543884.1 NZ_CP076498:72137-72232 [Enterococcus faecalis]
MYEIVTKILVPIFVGIVLKLVTIWLEKQNEE
MYEIVTKILVPIFVGIVLKLVTIWLEKQNEE
Download Length: 96 bp
>T205842 NZ_CP101915:c4204057-4203884 [Escherichia coli]
ATGGCACTATTCTCTAAAATATTAATTTTTTATGTGATTGGTGTGAACATATCCTTTGTCATTATCTGGTTTATCTCACA
TGAGAAAACACATATTCGTTTACTTAGTGCATTCCTGGTCGGAATAACCTGGCCAATGAGTCTGCCTGTGGCATTACTTT
TTTCTCTCTTTTAG
ATGGCACTATTCTCTAAAATATTAATTTTTTATGTGATTGGTGTGAACATATCCTTTGTCATTATCTGGTTTATCTCACA
TGAGAAAACACATATTCGTTTACTTAGTGCATTCCTGGTCGGAATAACCTGGCCAATGAGTCTGCCTGTGGCATTACTTT
TTTCTCTCTTTTAG
Antitoxin
Download Length: 65 bp
>AT205842 NZ_CP076498:c72331-72267 [Enterococcus faecalis]
CTTGTGACAAAGTCGTGCATGGATGCACTAAAAAGACACCCTATTGTGGTAGGGTGTCTTTTTTT
CTTGTGACAAAGTCGTGCATGGATGCACTAAAAAGACACCCTATTGTGGTAGGGTGTCTTTTTTT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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