Detailed information of TA system TA205838

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/Fst(toxin)
• Location: 396..637
• Replicon: plasmid pUAMSEL2
• Accession: NZ_CP076495
• Organism: Enterococcus faecalis strain UAMS_EL54

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: KPU55_RS15680
• Protein ID: WP_002360667.1
• Coordinates: 527..637 (-)
• Length: 37 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	396..487 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
- (396)	396..487	+	92	NuclAT_0	-	Antitoxin
- (396)	396..487	+	92	NuclAT_0	-	Antitoxin
- (396)	396..487	+	92	NuclAT_0	-	Antitoxin
- (396)	396..487	+	92	NuclAT_0	-	Antitoxin
KPU55_RS15680 (527)	527..637	-	111	WP_002360667.1	type I toxin-antitoxin system Fst family toxin	Toxin
KPU55_RS15685 (719)	719..931	-	213	WP_002360669.1	hypothetical protein	-
KPU55_RS15690 (888)	888..1238	-	351	WP_002400993.1	hypothetical protein	-
KPU55_RS15695 (1235)	1235..2563	-	1329	WP_002400994.1	ultraviolet resistance protein UvrA	-
KPU55_RS15700 (2991)	2991..3308	-	318	WP_224813313.1	DUF6440 family protein	-
KPU55_RS15705 (3576)	3576..3773	-	198	WP_048669782.1	hypothetical protein	-
KPU55_RS15710 (3807)	3807..4106	-	300	WP_142657760.1	BRCT domain-containing protein	-
KPU55_RS15715 (4147)	4147..4764	-	618	WP_025191668.1	recombinase family protein	-
KPU55_RS15720 (4969)	4969..5307	-	339	WP_049098551.1	type II toxin-antitoxin system PemK/MazF family toxin	-
KPU55_RS15725 (5304)	5304..5561	-	258	WP_010824092.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	EF0149	1..55304	55304

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 37 a.a.
• Molecular weight: 4117.92 Da
• Isoelectric Point: 4.1672

>T205838 WP_002360667.1 NZ_CP076495:c637-527 [Enterococcus faecalis]
VLFVKDLMSLVIAPIFVGLVLEMISRVLDEEDDNRK

Nucleotide

• Length: 111 bp

>T205838 NZ_CP101915:c3650078-3649680 [Escherichia coli]
ATGCGGGTATTCAAAACAAAACTTATTCGCCTGCAACTTACAGCAGAGGAACTTGATGCGTTAACGGCGGATTTTATTTC
CTATAAGCGTGACGGTGTTTTGCCAGATATATTTGGTCGCGATGCACTCTACGACGACTCCTTTACCTGGCCATTAATCA
AATTTGAGCGAGTTGCTCATATTCATCTGGCAAATGAGAATAATCCATTTCCGCCACAGTTGCGCCAATTCAGCAGAACG
AATGACGAAGCGCATTTGGTATATTGTCAGGGGGCGTTTGATGAGCAAGCATGGTTGCTCATTGCCATTCTGAAACCTGA
ACCTCATAAACTGGCTCGAGATAACAACCAAATGCATAAAATTGGGAAAATGGCAGAAGCGTTTCGCATGCGTTTTTGA

Antitoxin

Nucleotide

• Length: 92 bp

>AT205838 NZ_CP076495:396-487 [Enterococcus faecalis]
TAAAAATATGTTATACTAAAGGTGCGAAACGACATTAAATCGTACAAATAACACAAAAAGCAATCCTACGGCGAATAGGA
TTGCTTTTTTTT

Structures

Antitoxin