Detailed information of TA system TA205831

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/Fst(toxin)
• Location: 415..629
• Replicon: plasmid pUAMSEL1
• Accession: NZ_CP076494
• Organism: Enterococcus faecalis strain UAMS_EL54

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: KPU55_RS14935
• Protein ID: WP_002360667.1
• Coordinates: 519..629 (-)
• Length: 37 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	415..479 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
-	415..479	+	65	-	-	Antitoxin
KPU55_RS14935	519..629	-	111	WP_002360667.1	type I toxin-antitoxin system Fst family toxin	Toxin
KPU55_RS14940	711..923	-	213	Protein_2	excinuclease ABC subunit C	-
KPU55_RS14945	880..1230	-	351	WP_002360672.1	hypothetical protein	-
KPU55_RS14950	1227..2555	-	1329	WP_129268066.1	ultraviolet resistance protein UvrA	-
KPU55_RS14955	2984..3286	-	303	WP_002372577.1	DUF6440 family protein	-
KPU55_RS14960	3298..3507	-	210	WP_002382045.1	hypothetical protein	-
KPU55_RS14965	3568..3792	-	225	WP_002383635.1	ultraviolet resistance protein UvrA repressor UvrC	-
KPU55_RS14970	3786..4100	-	315	WP_002383634.1	hypothetical protein	-
KPU55_RS14975	4090..4197	-	108	Protein_9	recombinase family protein	-
KPU55_RS14980	4271..5432	+	1162	Protein_10	IS3 family transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	aph(3')-III / ant(6)-Ia / erm(B)	cylI / cylA / cylB / cylM / cylS / cylL / cylR1 / cylR2	1..119714	119714
	-	flank	IS/Tn	-	-	4596..5432	836

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 37 a.a.
• Molecular weight: 4117.92 Da
• Isoelectric Point: 4.1672

>T205831 WP_002360667.1 NZ_CP076494:c629-519 [Enterococcus faecalis]
VLFVKDLMSLVIAPIFVGLVLEMISRVLDEEDDNRK

Nucleotide

• Length: 111 bp

>T205831 NZ_CP101915:1978467-1978570 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin

Nucleotide

• Length: 65 bp

>AT205831 NZ_CP076494:415-479 [Enterococcus faecalis]
AACGACATTAAATCGTACAAATAACACAAAAAGCAATCCTACGGCGAATAGGATTGCTTTTTTTT

Structures

Antitoxin