Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2201216..2201479 Replicon chromosome
Accession NC_002951
Organism Staphylococcus aureus subsp. aureus COL

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag SACOL_RS11200 Protein ID WP_001802298.1
Coordinates 2201375..2201479 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2201216..2201380 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SACOL_RS11180 2197465..2198130 - 666 WP_001024094.1 SDR family oxidoreductase -
SACOL_RS11185 2198282..2198602 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
SACOL_RS11190 2198604..2199584 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
SACOL_RS11195 2199850..2200941 + 1092 WP_000495671.1 lytic regulatory protein -
- 2201216..2201380 + 165 - - Antitoxin
SACOL_RS11200 2201375..2201479 - 105 WP_001802298.1 hypothetical protein Toxin
SACOL_RS15140 2201640..2202123 - 484 Protein_2115 recombinase family protein -
SACOL_RS11210 2202166..2203302 - 1137 WP_000115564.1 SAP domain-containing protein -
SACOL_RS11215 2203591..2203683 + 93 WP_001790138.1 hypothetical protein -
SACOL_RS11220 2204388..2205245 - 858 WP_033841791.1 Cof-type HAD-IIB family hydrolase -
SACOL_RS11225 2205313..2206095 - 783 WP_000908177.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T20582 WP_001802298.1 NC_002951:c2201479-2201375 [Staphylococcus aureus subsp. aureus COL]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T20582 NC_002951:c2201479-2201375 [Staphylococcus aureus subsp. aureus COL]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT20582 NC_002951:2201216-2201380 [Staphylococcus aureus subsp. aureus COL]
GTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References