Detailed information of TA system TA205814

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/-
• Location: 2492619..2492813
• Replicon: chromosome
• Accession: NZ_CP076493
• Organism: Enterococcus faecalis strain UAMS_EL54

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: KPU55_RS12105
• Protein ID: WP_015543884.1
• Coordinates: 2492619..2492714 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	2492749..2492813 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KPU55_RS12085	2487798..2488913	+	1116	WP_002379062.1	FAD-dependent oxidoreductase	-
KPU55_RS12090	2488980..2490134	-	1155	WP_002355280.1	mannitol-1-phosphate 5-dehydrogenase	-
KPU55_RS12095	2490149..2490586	-	438	WP_002355279.1	PTS sugar transporter subunit IIA	-
KPU55_RS12100	2490601..2492373	-	1773	WP_010706745.1	PTS mannitol-specific transporter subunit IIBC	-
KPU55_RS12105	2492619..2492714	+	96	WP_015543884.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	2492749..2492813	-	65	-	-	Antitoxin
KPU55_RS12110	2492969..2493403	-	435	WP_002358391.1	PTS sugar transporter subunit IIA	-
KPU55_RS12115	2493414..2495447	-	2034	WP_002387671.1	PRD domain-containing protein	-
KPU55_RS12120	2495438..2497180	-	1743	WP_002399652.1	PTS transporter subunit EIIC	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3659.47 Da
• Isoelectric Point: 4.6275

>T205814 WP_015543884.1 NZ_CP076493:2492619-2492714 [Enterococcus faecalis]
MYEIVTKILVPIFVGIVLKLVTIWLEKQNEE

Nucleotide

• Length: 96 bp

>T205814 NZ_CP101912:2691833-2692408 [Pseudomonas aeruginosa]
ATGAGGCATTCCCCATTCACCGCCGTCTACGACGCGTGCGTTCTATATCCCGCGCCACTGCGGGATTTCCTGATGTGGCT
CGGCCTGTCTGGCCGCTTCCGGGCGCGGTGGAGCCAAGCCATTCATGAGGAGTGGAAACGCAACCTGTTGATCAACCGCC
CCGATCTCACCCGGGTTCAGGTCGACAGGACGTCGGATCTCATGGACAGGGCCATTCCGGACGGCTTGGTGGAGGGCTAC
GAAGCGCTCGTGGCAGGCCTGACATTACCCGATCCGAATGATCGGCACGTCCTGGCTGCGGCGATTCGCTGCGGTGCGAG
CGTGATTGTGACGTTCAACGAACGTGATTTCCCGAACGATCTGCTGGCTCCGTACGGCATCGAATCGCAGCACCCCGATG
AGTTTGTGGACAACCTGCTGGATCTGGATGCGGCCGCCGTAGTGTCGGCTGCGCAGCGCCAGCGTGCCCAACTCAAGCAT
CCGCCGATCGATGTGGACCGCTATCTCGAAATCCTGCTGCGCCAAGGCCTTGTGCAAACGACCAAGGTGCTGGCGACCTA
TCGCACCATTCTCTGA

Antitoxin

Nucleotide

• Length: 65 bp

>AT205814 NZ_CP076493:c2492813-2492749 [Enterococcus faecalis]
CTTGTGACAAAGTCGTGCATGGATGCACTAAAAAGACACCCTATTGTGGTAGGGTGTCTTTTTTT

Structures

Antitoxin