Detailed information of TA system TA205798

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/Fst(toxin)
• Location: 372..613
• Replicon: plasmid pUAMSEL2
• Accession: NZ_CP076490
• Organism: Enterococcus faecalis strain UAMS_EL56

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: KPU60_RS15660
• Protein ID: WP_002360667.1
• Coordinates: 503..613 (-)
• Length: 37 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	372..463 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
- (372)	372..463	+	92	NuclAT_0	-	Antitoxin
- (372)	372..463	+	92	NuclAT_0	-	Antitoxin
- (372)	372..463	+	92	NuclAT_0	-	Antitoxin
- (372)	372..463	+	92	NuclAT_0	-	Antitoxin
KPU60_RS15660 (503)	503..613	-	111	WP_002360667.1	type I toxin-antitoxin system Fst family toxin	Toxin
KPU60_RS15665 (695)	695..907	-	213	WP_002360669.1	hypothetical protein	-
KPU60_RS15670 (864)	864..1214	-	351	WP_002400993.1	hypothetical protein	-
KPU60_RS15675 (1211)	1211..2539	-	1329	WP_002400994.1	ultraviolet resistance protein UvrA	-
KPU60_RS15680 (2967)	2967..3284	-	318	WP_224813313.1	DUF6440 family protein	-
KPU60_RS15685 (3552)	3552..3749	-	198	WP_048669782.1	hypothetical protein	-
KPU60_RS15690 (3783)	3783..4082	-	300	WP_142657760.1	BRCT domain-containing protein	-
KPU60_RS15695 (4123)	4123..4740	-	618	WP_025191668.1	recombinase family protein	-
KPU60_RS15700 (4945)	4945..5283	-	339	WP_049098551.1	type II toxin-antitoxin system PemK/MazF family toxin	-
KPU60_RS15705 (5280)	5280..5537	-	258	WP_010824092.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	EF0149	1..55288	55288

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 37 a.a.
• Molecular weight: 4117.92 Da
• Isoelectric Point: 4.1672

>T205798 WP_002360667.1 NZ_CP076490:c613-503 [Enterococcus faecalis]
VLFVKDLMSLVIAPIFVGLVLEMISRVLDEEDDNRK

Nucleotide

• Length: 111 bp

>T205798 NZ_CP101910:c1330142-1329864 [Pseudomonas putida]
ATAATTCAAAGCTTTAGCTGTGCCGACACGGAAGCGCTCTTCACAACGGGAAAGACACGGCGTTGTTCAGATATCAAGTC
AGTCGCGGAGCGCAAACTGGCCATGCTCGATGCCGCAACAGCGTTGCGAGACCTTAGGTCGCCACCTGGCAACCGCCTCG
AGTCACTGAGCGGCGACCGCGCCGGCCAACACAGTATCCGTGTAAATGACCAATGGCGGCTGTGCTTCACCTGGACAGAA
CACGGGCCAATTAACGTTGAAATTGTCGATTACCACTGA

Antitoxin

Nucleotide

• Length: 92 bp

>AT205798 NZ_CP076490:372-463 [Enterococcus faecalis]
TAAAAATATGTTATACTAAAGGTGCGAAACGACATTAAATCGTACAAATAACACAAAAAGCAATCCTACGGCGAATAGGA
TTGCTTTTTTTT

Structures

Antitoxin