Detailed information of TA system TA205794

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/Fst(toxin)
• Location: 75855..76069
• Replicon: plasmid pUAMSEL1
• Accession: NZ_CP076489
• Organism: Enterococcus faecalis strain UAMS_EL56

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: KPU60_RS15375
• Protein ID: WP_002360667.1
• Coordinates: 75959..76069 (-)
• Length: 37 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	75855..75919 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KPU60_RS15345	71494..71682	-	189	Protein_86	hypothetical protein	-
KPU60_RS15350	71607..72590	-	984	WP_000007382.1	prolipoprotein diacylglyceryl transferase	-
KPU60_RS15355	72634..73644	-	1011	WP_001058676.1	replication initiator protein A	-
KPU60_RS15360	74116..74961	+	846	WP_000239313.1	AAA family ATPase	-
KPU60_RS15365	74954..75325	+	372	WP_000049959.1	replication-associated protein RepC	-
KPU60_RS15370	75429..75719	-	291	WP_001137528.1	hypothetical protein	-
-	75855..75919	+	65	-	-	Antitoxin
KPU60_RS15375	75959..76069	-	111	WP_002360667.1	type I toxin-antitoxin system Fst family toxin	Toxin
KPU60_RS15380	76151..76363	-	213	Protein_93	excinuclease ABC subunit C	-
KPU60_RS15385	76320..76670	-	351	WP_002360672.1	hypothetical protein	-
KPU60_RS15390	76667..77995	-	1329	WP_129268066.1	ultraviolet resistance protein UvrA	-
KPU60_RS15395	78424..78726	-	303	WP_002372577.1	DUF6440 family protein	-
KPU60_RS15400	78738..78947	-	210	WP_002382045.1	hypothetical protein	-
KPU60_RS15405	79008..79232	-	225	WP_002383635.1	ultraviolet resistance protein UvrA repressor UvrC	-
KPU60_RS15410	79226..79540	-	315	WP_002383634.1	hypothetical protein	-
KPU60_RS15415	79530..79637	-	108	Protein_100	recombinase family protein	-
KPU60_RS15420	79711..80872	+	1162	Protein_101	IS3 family transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	aph(3')-III / ant(6)-Ia / erm(B)	cylI / cylA / cylB / cylM / cylS / cylL / cylR1 / cylR2	1..119713	119713
	-	flank	IS/Tn	-	-	80036..80872	836

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 37 a.a.
• Molecular weight: 4117.92 Da
• Isoelectric Point: 4.1672

>T205794 WP_002360667.1 NZ_CP076489:c76069-75959 [Enterococcus faecalis]
VLFVKDLMSLVIAPIFVGLVLEMISRVLDEEDDNRK

Nucleotide

• Length: 111 bp

>T205794 NZ_CP101908:c14266-13916 [Salmonella enterica subsp. enterica]
ATGTGGGTCATCGAGACAACCGACACCTTTGATGAGTGGTTCGATGCTCTGGATGATACCGATAGAGCAAACGTGCTGGC
TTCGATGATGGTGCTGCGAGATAGAGGCCCCATGCTGTCGAGGCCATACGCGGATACTGTTAACGGTTCATCCTACAGCA
ACATGAAAGAGCTTCGGGTCCAAAGCAAAGGAGATCCTATCAGAGCGTTCTTTGCGTTCGATCCAAAGCGTAAGGGGATT
CTTCTCTGCGCCGGTAACAAGACCGGGGACGAGAAAAGGTTTTATGAAGTAATGATCCCAATTGCAGACCGTGAGTTTGC
GGCGCACTTGGATAAATTGAAGAAGGAGTGA

Antitoxin

Nucleotide

• Length: 65 bp

>AT205794 NZ_CP076489:75855-75919 [Enterococcus faecalis]
AACGACATTAAATCGTACAAATAACACAAAAAGCAATCCTACGGCGAATAGGATTGCTTTTTTTT

Structures

Antitoxin