Detailed information of TA system TA205787

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/-
• Location: 2942585..2942779
• Replicon: chromosome
• Accession: NZ_CP076488
• Organism: Enterococcus faecalis strain UAMS_EL56

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: KPU60_RS14430
• Protein ID: WP_015543884.1
• Coordinates: 2942585..2942680 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	2942715..2942779 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KPU60_RS14410	2937764..2938879	+	1116	WP_002379062.1	FAD-dependent oxidoreductase	-
KPU60_RS14415	2938946..2940100	-	1155	WP_002355280.1	mannitol-1-phosphate 5-dehydrogenase	-
KPU60_RS14420	2940115..2940552	-	438	WP_002355279.1	PTS sugar transporter subunit IIA	-
KPU60_RS14425	2940567..2942339	-	1773	WP_010706745.1	PTS mannitol-specific transporter subunit IIBC	-
KPU60_RS14430	2942585..2942680	+	96	WP_015543884.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	2942715..2942779	-	65	-	-	Antitoxin
KPU60_RS14435	2942935..2943369	-	435	WP_002358391.1	PTS sugar transporter subunit IIA	-
KPU60_RS14440	2943380..2945413	-	2034	WP_002387671.1	PRD domain-containing protein	-
KPU60_RS14445	2945404..2947146	-	1743	WP_002399652.1	PTS transporter subunit EIIC	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3659.47 Da
• Isoelectric Point: 4.6275

>T205787 WP_015543884.1 NZ_CP076488:2942585-2942680 [Enterococcus faecalis]
MYEIVTKILVPIFVGIVLKLVTIWLEKQNEE

Nucleotide

• Length: 96 bp

>T205787 NZ_CP101907:c2894751-2894440 [Salmonella enterica subsp. enterica]
ATGCAATTTATAGAAACGGAACTCTTTACTGAAGATGTTAAAAAACTGCTCGATGATGATGAATACCATAAGCTTCAGGT
TTTTATGGCTCAGCATCCAGATTGTGGTGATGTCATTCAGGAAACGGGCGGCCTGAGAAAAATGCGCTGGGGAGCGCGAG
GCAAAGGAAAGCGTAGTGGCGTGCGAATTATCTATTTTCACCGTAGTCAACGGTATGAGATTCGCTTGCTTCTGATTTAT
CAAAAAGGCATTAAAGATGATCTCACGCCGCAGGAAAAAGCGGTGCTTCGTATGCTGAATGAGAGGTGGTAG

Antitoxin

Nucleotide

• Length: 65 bp

>AT205787 NZ_CP076488:c2942779-2942715 [Enterococcus faecalis]
CTTGTGACAAAGTCGTGCATGGATGCACTAAAAAGACACCCTATTGTGGTAGGGTGTCTTTTTTT

Structures

Antitoxin