Detailed information of TA system TA205775

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-RNAII/-
• Location: 579973..580232
• Replicon: chromosome
• Accession: NZ_CP076488
• Organism: Enterococcus faecalis strain UAMS_EL56

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: KPU60_RS02930
• Protein ID: WP_021164442.1
• Coordinates: 579973..580074 (+)
• Length: 34 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	580028..580232 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KPU60_RS02915	575384..576280	-	897	WP_002354953.1	YitT family protein	-
KPU60_RS02920	576841..577341	-	501	WP_002378961.1	cysteine hydrolase family protein	-
KPU60_RS02925	577512..579782	+	2271	WP_002399785.1	bifunctional glutamate--cysteine ligase/glutathione synthetase	-
KPU60_RS02930	579973..580074	+	102	WP_021164442.1	putative holin-like toxin	Toxin
-	580028..580232	-	205	-	-	Antitoxin
KPU60_RS02935	580407..580508	+	102	WP_021164441.1	putative holin-like toxin	-
KPU60_RS02940	580690..581142	-	453	WP_002378959.1	YueI family protein	-
KPU60_RS02945	581327..582274	+	948	WP_002354960.1	iron chelate uptake ABC transporter family permease subunit	-
KPU60_RS02950	582271..583236	+	966	WP_002387376.1	iron chelate uptake ABC transporter family permease subunit	-
KPU60_RS02955	583233..583988	+	756	WP_002354962.1	ATP-binding cassette domain-containing protein	-
KPU60_RS02960	584027..584980	+	954	WP_002370087.1	siderophore ABC transporter substrate-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-33)

Sequences

Toxin

Protein

• Length: 34 a.a.
• Molecular weight: 3625.38 Da
• Isoelectric Point: 4.5869

>T205775 WP_021164442.1 NZ_CP076488:579973-580074 [Enterococcus faecalis]
MSIEATLELMISFATLVALLIFGILEATKNDKK

Nucleotide

• Length: 102 bp

>T205775 NZ_CP101885:2356627-2357382 [Pseudomonas aeruginosa]
GTGAGCGAGATCTGGCGACAGTGCAAGGGTGAGCGGCATGTCCGACCGCTCCAGGGGCGGCTGGTGCGGTTGGTGGAGAG
CCAGGAGCAGGTGGCGACCCTGCAATTGGTCGACACCCTGGAAGAACAGGCGTTGCTCGAGGAACTGCTCGAGTCGAGCA
AGCCGCCGGTGCCGGCGGATGCCGAGCCATTGCATTACCTGTTGAAGACCCCGTTCCGTTATCCGCCCTTGCGTTGGGGG
TCGCGGTTTGGCCGTCGTCACGAGCCAAGCCTGTTCTACGCCGCGTTGAAGCTGGAAACGGCCATGGCCGAAAGCGCGTA
TTACCGTTGTGTCCTGTGGAGTGGCATGGCGGTGCCGCCACCGAGCGGGAGGATTCTGTCCGAGCACGCTTCGTTCGAGG
CGGGCTGGAAGGTGGAGCGGGGAATCCGTCTGCAGGCGCCGCCTTTCTCCGATCACGAGGCTGCGCTGACCGACATCGCC
GACTACCGCGCTCCCCAGGAACTGGGAAGTGCCATGCGCAGCGCCGGGGTGCAGGCATTCGAATACCGTTCGGCGCGTTG
CCCGGAGCGCGGCTGCAATGTCGCCCTGTTCACGCCCGCGGCCTTCACCGAAAAGCGTCCTCGCAACCTGACGCCCTGGC
TGTGCGAAACCACGGCCGGTTACGTGGCCTTCAAGCCGGCGCATGTGCCGGGGTCGCCGAAAATCTTCTCCTGGGAGCTG
TTCCTGGTGGACGGAAAGTTGCCGCATCCGGCGTGA

Antitoxin

Nucleotide

• Length: 205 bp

>AT205775 NZ_CP076488:c580232-580028 [Enterococcus faecalis]
TTCCATTTTAAATAGAATTATGCTATTATGAAAATGAAAAGAGAGATATGCTACTACATACCTCTCCTTTATACCAACAC
CAGTTATAAGAACTGGTGGCTTACTGAGTTAAGTTTTTGTTGTTCTTTAACCGTTCAGCCGTCTAAGCTTATGAACGGTT
ATTTTTTATCGTTTTTCGTTGCTTCAAGGATACCGAAAATCAGTA

Structures

Antitoxin