Detailed information of TA system
Overview
TA module
| Type | I | Classification (family/domain) | symER/SymE(toxin) |
| Location | 1170870..1171282 | Replicon | chromosome |
| Accession | NZ_CP076470 | ||
| Organism | Escherichia coli strain DH5a | ||
Toxin (Protein)
| Gene name | symE | Uniprot ID | U9YSY7 |
| Locus tag | KN807_RS05730 | Protein ID | WP_000132601.1 |
| Coordinates | 1170941..1171282 (+) | Length | 114 a.a. |
Antitoxin (RNA)
| Gene name | symR | ||
| Locus tag | - | ||
| Coordinates | 1170870..1170946 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KN807_RS05720 (1167733) | 1167733..1169322 | + | 1590 | WP_001063204.1 | type I restriction-modification system methyltransferase | - |
| KN807_RS05725 (1169319) | 1169319..1170713 | + | 1395 | WP_001272447.1 | type I restriction-modification system specificity subunit | - |
| - (1170870) | 1170870..1170946 | - | 77 | NuclAT_14 | - | Antitoxin |
| - (1170870) | 1170870..1170946 | - | 77 | NuclAT_14 | - | Antitoxin |
| - (1170870) | 1170870..1170946 | - | 77 | NuclAT_14 | - | Antitoxin |
| - (1170870) | 1170870..1170946 | - | 77 | NuclAT_14 | - | Antitoxin |
| - (1170870) | 1170870..1170946 | - | 77 | NuclAT_15 | - | Antitoxin |
| - (1170870) | 1170870..1170946 | - | 77 | NuclAT_15 | - | Antitoxin |
| - (1170870) | 1170870..1170946 | - | 77 | NuclAT_15 | - | Antitoxin |
| - (1170870) | 1170870..1170946 | - | 77 | NuclAT_15 | - | Antitoxin |
| KN807_RS05730 (1170941) | 1170941..1171282 | + | 342 | WP_000132601.1 | endoribonuclease SymE | Toxin |
| KN807_RS05735 (1171444) | 1171444..1172823 | + | 1380 | WP_000443951.1 | 5-methylcytosine-specific restriction endonuclease subunit McrB | - |
| KN807_RS05740 (1172823) | 1172823..1173869 | + | 1047 | WP_000437621.1 | 5-methylcytosine-specific restriction endonuclease system specificity protein McrC | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 114 a.a. Molecular weight: 12203.02 Da Isoelectric Point: 8.5012
>T205722 WP_000132601.1 NZ_CP076470:1170941-1171282 [Escherichia coli]
MTDTHSIAQPFEAEVSPANNRHVTVGYASRYPDYSRIPAITLKGQWLEAAGFATGTAVDVKVMEGCIVLTAQPPAAEESE
LMQSLRQVCKLSARKQKQVQAFIGVIAGKQKVA
MTDTHSIAQPFEAEVSPANNRHVTVGYASRYPDYSRIPAITLKGQWLEAAGFATGTAVDVKVMEGCIVLTAQPPAAEESE
LMQSLRQVCKLSARKQKQVQAFIGVIAGKQKVA
Download Length: 342 bp
>T205722 NZ_CP101858:c2750383-2750153 [Escherichia coli]
CTGGATCAGCTATTTAAATCACCTTTACCTCAAGGAATCAAATGGACTGATATAGAATCTCTGGTTAAAGCGTTAGGCGG
AGAAATTAAGGAAGGTAGGGGGTCGCGCTGTAAGTTCATACTAAATATGAGCGTTGCGTGTTTCCATCGGCCTCATCCGT
CGCCAGATACCGATAAAGGCGCTGTAGAAAGCGTGCGTGACTGGTTACTAAGTATAGGGGTAAAACCATGA
CTGGATCAGCTATTTAAATCACCTTTACCTCAAGGAATCAAATGGACTGATATAGAATCTCTGGTTAAAGCGTTAGGCGG
AGAAATTAAGGAAGGTAGGGGGTCGCGCTGTAAGTTCATACTAAATATGAGCGTTGCGTGTTTCCATCGGCCTCATCCGT
CGCCAGATACCGATAAAGGCGCTGTAGAAAGCGTGCGTGACTGGTTACTAAGTATAGGGGTAAAACCATGA
Antitoxin
Download Length: 77 bp
>AT205722 NZ_CP076470:c1170946-1170870 [Escherichia coli]
AGTCATAACTGCTATTCTCCAGGAATAGTGATTGTGATTAGCGATGCGGGTGTGTTGGCGCACATCCGCACCGCGCT
AGTCATAACTGCTATTCTCCAGGAATAGTGATTGTGATTAGCGATGCGGGTGTGTTGGCGCACATCCGCACCGCGCT
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
