Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 1784184..1784887 Replicon chromosome
Accession NZ_CP076412
Organism Ralstonia wenshanensis strain 56D2

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag KOL96_RS07925 Protein ID WP_232039373.1
Coordinates 1784184..1784483 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag KOL96_RS07930 Protein ID WP_232039374.1
Coordinates 1784486..1784887 (+) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KOL96_RS07910 (KOL96_07855) 1779561..1781531 + 1971 WP_232040253.1 TonB-dependent receptor -
KOL96_RS07915 (KOL96_07860) 1781528..1782100 + 573 WP_232039371.1 YfiR family protein -
KOL96_RS07920 (KOL96_07865) 1782097..1784109 + 2013 WP_232039372.1 EAL domain-containing protein -
KOL96_RS07925 (KOL96_07870) 1784184..1784483 + 300 WP_232039373.1 type II toxin-antitoxin system MqsR family toxin Toxin
KOL96_RS07930 (KOL96_07875) 1784486..1784887 + 402 WP_232039374.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
KOL96_RS07935 (KOL96_07880) 1784948..1785835 - 888 WP_232039375.1 EamA family transporter -
KOL96_RS07940 (KOL96_07885) 1786230..1787870 - 1641 WP_232039376.1 rhodanese-related sulfurtransferase -
KOL96_RS07945 (KOL96_07890) 1787867..1788514 - 648 WP_232039377.1 cysteine dioxygenase -
KOL96_RS07950 (KOL96_07895) 1788765..1789130 - 366 WP_232039378.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(2-98)

Antitoxin

Antitoxin MqsA

(3-130)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11103.96 Da        Isoelectric Point: 9.0755

>T205675 WP_232039373.1 NZ_CP076412:1784184-1784483 [Ralstonia wenshanensis]
MEKRTPHAKLSLVRELIRSGSVRATRSAYEGALELGITDLAGMCAVVMTLTPHCFYKSMTTHADHRVWQDVYHAKARGQD
IYLKLTVVDGVLIVSFKEL

Download         Length: 300 bp

>T205675 NZ_CP101794:c182477-181995 [Klebsiella pneumoniae]
ATGGGAATGAGAGCGCCTGAATCCCTGATGTCTGAACATAACATCGCTGAGTTCTGCTGCCAGGAGCCTGCCCTTAATGA
GTGGTTAAAGAAGAAGGCTCTCAGAAACCACAGTACCGGCATTTCCCGTGTCTATGTCGTCTGCGCAGAAAACACTAACC
GGGTCATCGGTTATTATTGTTTATCTTCGGGTAGCGTCCACCGTAACACAGTGCCTGGGGCCTATAGACGCAACGCGCCT
GATGTCATTCCAGTCATTGTTTTGGGACGGCTTGCCATCGACCAGGCCTGGGCCGGAAATGGGCTTGGTGCCGCACTTCT
TAAGGATGCTATATACCGTACGCAAAACATAGCCTTTCAGGTCGGGGTGAGAGCACTGGCCGTGCATGCGCTGAATGAAG
AAGTTAAATGTTTTTACACCCGTTTTGGCTTTGAGCCTTCCATAGTCAACACGCTGACATTGTTATTCCCGATAAAAGTC
TGA

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14599.66 Da        Isoelectric Point: 5.6776

>AT205675 WP_232039374.1 NZ_CP076412:1784486-1784887 [Ralstonia wenshanensis]
MKCPSCGAAELIHDTRDVPYVYKGEATVIPSVTGDFCPACDEIVLERGEGDRYGELVSAFQRQVNSAYIDPAYIATVRRK
LNLDQREAAEIFGGGVNAFSRYETGKTKPSLALVKLLKLLDHHPDLLAEIKTA

Download         Length: 402 bp

>AT205675 NZ_CP101794:c182746-182468 [Klebsiella pneumoniae]
ATGAAACCAGACGTTCGTGAAGCTCCGATTAATATCCGGGCCAAAACATCACAGCGTGACCTGATCGACATGGCCGCAAG
CCTGGTCTCAAAATCACGGACTGATTTTATGCTTGAGGTTGCCTGCAGGGAGGCACAGGACATTCTGCTTGATCAACGCC
TGTTCCTCCTCAATGACAATCAGTTTGAGGCGTTTATTGAAGAGCTTGACGCCCCAATAACACCGGAGCGCCAGGCGCGA
ATCGATAACCTGATGAACCGCAAATCACCATGGGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References