Detailed information of TA system TA205396

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): yonT-as-bsrG/-
• Location: 2311859..2312071
• Replicon: chromosome
• Accession: NZ_CP076290
• Organism: Bacillus velezensis strain Q12

Toxin (Protein)

• Gene name: yonT
• Uniprot ID: -
• Locus tag: KM776_RS11385
• Protein ID: WP_165882033.1
• Coordinates: 2311859..2312038 (-)
• Length: 60 a.a.

Antitoxin (RNA)

Gene name	as-bsrG
Locus tag	-
Coordinates	2311985..2312071 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KM776_RS11370 (2307828)	2307828..2309696	-	1869	WP_215601718.1	hypothetical protein	-
KM776_RS11375 (2310004)	2310004..2311236	-	1233	WP_215601719.1	hypothetical protein	-
KM776_RS11380 (2311317)	2311317..2311556	-	240	WP_165882034.1	hypothetical protein	-
KM776_RS11385 (2311859)	2311859..2312038	-	180	WP_165882033.1	hypothetical protein	Toxin
- (2311985)	2311985..2312071	+	87	NuclAT_1	-	Antitoxin
- (2311985)	2311985..2312071	+	87	NuclAT_1	-	Antitoxin
- (2311985)	2311985..2312071	+	87	NuclAT_1	-	Antitoxin
- (2311985)	2311985..2312071	+	87	NuclAT_1	-	Antitoxin
KM776_RS11390 (2313052)	2313052..2314542	+	1491	WP_215601720.1	PIN-like domain-containing protein	-
KM776_RS11395 (2314606)	2314606..2315718	-	1113	WP_215601721.1	cell division protein FtsZ	-
KM776_RS11400 (2315718)	2315718..2316002	-	285	WP_053574271.1	hypothetical protein	-
KM776_RS11405 (2316181)	2316181..2316417	+	237	WP_020954165.1	helix-turn-helix domain-containing protein	-
KM776_RS11410 (2316537)	2316537..2316716	+	180	WP_014417885.1	hypothetical protein	-
KM776_RS11415 (2316790)	2316790..2317026	+	237	WP_160228964.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2235661..2375031	139370

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Sequences

Toxin

Protein

• Length: 60 a.a.
• Molecular weight: 7040.71 Da
• Isoelectric Point: 12.4499

>T205396 WP_165882033.1 NZ_CP076290:c2312038-2311859 [Bacillus velezensis]
VLEKVGIAIAFLIPITVLIINCLTIAEKIQNLMKNKESKKKKRTRKRLRSKRQRKRIRR

Nucleotide

• Length: 180 bp

>T205396 NZ_CP101615:2639941-2640048 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCGGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin

Nucleotide

• Length: 87 bp

>AT205396 NZ_CP076290:2311985-2312071 [Bacillus velezensis]
TAAAACCGTGATAGGAATAAGGAAAGCAATTGCTATACCCACTTTCTCAAGCACTATGTACACCTCCTTTCCTATAACTC
TATTATA

Structures

Antitoxin